Ashton MJ - Search Results

1

New low-density lipoprotein receptor upregulators acting via a novel mechanism.

Ashton MJ, Brown TJ, Fenton G, Halley F, Harper MF, Lockey PM, Porter B, Roach AG, Stuttle KA, Vicker N, Walsh RJ. Ashton MJ, et al. J Med Chem. 1996 Aug 16;39(17):3343-56. doi: 10.1021/jm960153q. J Med Chem. 1996. PMID: 8765518

2

Anti-inflammatory 17beta-thioalkyl-16alpha,17alpha-ketal and -acetal androstanes: a new class of airway selective steroids for the treatment of asthma.

Ashton MJ, Lawrence C, Karlsson JA, Stuttle KA, Newton CG, Vacher BY, Webber S, Withnall MJ. Ashton MJ, et al. J Med Chem. 1996 Dec 6;39(25):4888-96. doi: 10.1021/jm9604639. J Med Chem. 1996. PMID: 8960547

3

Acyl-CoA:cholesterol O-acyl transferase (ACAT) inhibitors. 1. 2-(Alkylthio)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.

Harris NV, Smith C, Ashton MJ, Bridge AW, Bush RC, Coffee EC, Dron DI, Harper MF, Lythgoe DJ, Newton CG, et al. Harris NV, et al. Among authors: ashton mj. J Med Chem. 1992 Nov 13;35(23):4384-92. doi: 10.1021/jm00101a016. J Med Chem. 1992. PMID: 1447739

4

Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues.

Ashton MJ, Cook DC, Fenton G, Karlsson JA, Palfreyman MN, Raeburn D, Ratcliffe AJ, Souness JE, Thurairatnam S, Vicker N. Ashton MJ, et al. J Med Chem. 1994 May 27;37(11):1696-703. doi: 10.1021/jm00037a021. J Med Chem. 1994. PMID: 8201604

5

Acyl-CoA:Cholesterol O-acyltransferase (ACAT) inhibitors. 2. 2-(1,3-Dioxan-2-yl)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.

Astles PC, Ashton MJ, Bridge AW, Harris NV, Hart TW, Parrott DP, Porter B, Riddell D, Smith C, Williams RJ. Astles PC, et al. Among authors: ashton mj. J Med Chem. 1996 Mar 29;39(7):1423-32. doi: 10.1021/jm9505876. J Med Chem. 1996. PMID: 8691472

6

Heterocyclic analogues of chlorcyclizine with potent hypolipidemic activity.

Ashton MJ, Ashford A, Loveless AH, Riddell D, Salmon J, Stevenson GV. Ashton MJ, et al. J Med Chem. 1984 Oct;27(10):1245-53. doi: 10.1021/jm00376a002. J Med Chem. 1984. PMID: 6148419

7

Acylthioxanthenes: agents which selectively reduce decerebrate rigidity in the cat.

Ashton MJ, Chapman RF, Loveless AH. Ashton MJ, et al. J Med Chem. 1980 Jun;23(6):653-7. doi: 10.1021/jm00180a014. J Med Chem. 1980. PMID: 7392031

8

Suppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP-specific phosphodiesterase: comparison with rolipram.

Souness JE, Maslen C, Webber S, Foster M, Raeburn D, Palfreyman MN, Ashton MJ, Karlsson JA. Souness JE, et al. Among authors: ashton mj. Br J Pharmacol. 1995 May;115(1):39-46. doi: 10.1111/j.1476-5381.1995.tb16317.x. Br J Pharmacol. 1995. PMID: 7647982 Free PMC article.

9

Effect of sodium 2-n-pentadecyl-benzimidazole-5-carboxylate (M & B 35347B), an inhibitor of acetyl-CoA carboxylase, on lipogenesis and fat deposition in obese hyperglycaemic (ob/ob) and lean mice.

Whittington FM, Enser M, Pratt J, Riddell D, Ashton MJ. Whittington FM, et al. Among authors: ashton mj. Int J Obes. 1987;11(6):619-29. Int J Obes. 1987. PMID: 2894366

10

Time marches on, but do the causal pathways driving instream habitat and biology remain consistent?

Walker RH, Ashton MJ, Cashman MJ, Fanelli RM, Krause KP, Noe GB, Maloney KO. Walker RH, et al. Among authors: ashton mj. Sci Total Environ. 2021 Oct 1;789:147985. doi: 10.1016/j.scitotenv.2021.147985. Epub 2021 May 24. Sci Total Environ. 2021. PMID: 34323823 Free article.

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