Huang JC - Search Results

1

Synthesis and structure-activity relationships of 1,2,3,4-tetrahydroquinoline-2,3,4-trione 3-oximes: novel and highly potent antagonists for NMDA receptor glycine site.

Cai SX, Zhou ZL, Huang JC, Whittemore ER, Egbuwoku ZO, Lü Y, Hawkinson JE, Woodward RM, Weber E, Keana JF. Cai SX, et al. Among authors: huang jc. J Med Chem. 1996 Aug 16;39(17):3248-55. doi: 10.1021/jm960214k. J Med Chem. 1996. PMID: 8765507

2

Enaminone amides as novel orally active GABAA receptor modulators.

Hogenkamp DJ, Johnstone TB, Huang JC, Li WY, Tran M, Whittemore ER, Bagnera RE, Gee KW. Hogenkamp DJ, et al. Among authors: huang jc. J Med Chem. 2007 Jul 12;50(14):3369-79. doi: 10.1021/jm070083v. Epub 2007 Jun 16. J Med Chem. 2007. PMID: 17571865

3

Synthesis and structure-activity relationships of substituted 1,4-dihydroquinoxaline-2,3-diones: antagonists of N-methyl-D-aspartate (NMDA) receptor glycine sites and non-NMDA glutamate receptors.

Keana JF, Kher SM, Cai SX, Dinsmore CM, Glenn AG, Guastella J, Huang JC, Ilyin V, Lü Y, Mouser PL, et al. Keana JF, et al. Among authors: huang jc. J Med Chem. 1995 Oct 27;38(22):4367-79. doi: 10.1021/jm00022a003. J Med Chem. 1995. PMID: 7473565

4

Structure-activity relationships of 4-hydroxy-3-nitroquinolin-2(1H)-ones as novel antagonists at the glycine site of N-methyl-D-aspartate receptors.

Cai SX, Zhou ZL, Huang JC, Whittemore ER, Egbuwoku ZO, Hawkinson JE, Woodward RM, Weber E, Keana JF. Cai SX, et al. Among authors: huang jc. J Med Chem. 1996 Nov 8;39(23):4682-6. doi: 10.1021/jm960520y. J Med Chem. 1996. PMID: 8917657

5

5-(N-oxyaza)-7-substituted-1,4-dihydroquinoxaline-2,3-diones: novel, systemically active and broad spectrum antagonists for NMDA/glycine, AMPA, and kainate receptors.

Cai SX, Huang JC, Espitia SA, Tran M, Ilyin VI, Hawkinson JE, Woodward RM, Weber E, Keana JF. Cai SX, et al. Among authors: huang jc. J Med Chem. 1997 Oct 24;40(22):3679-86. doi: 10.1021/jm970396y. J Med Chem. 1997. PMID: 9357535

6

Structure-activity relationships for a series of bis(phenylalkyl)amines: potent subtype-selective inhibitors of N-methyl-D-aspartate receptors.

Tamiz AP, Whittemore ER, Zhou ZL, Huang JC, Drewe JA, Chen JC, Cai SX, Weber E, Woodward RM, Keana JF. Tamiz AP, et al. Among authors: huang jc. J Med Chem. 1998 Aug 27;41(18):3499-506. doi: 10.1021/jm980235+. J Med Chem. 1998. PMID: 9719603

7

Limiting activity at beta1-subunit-containing GABAA receptor subtypes reduces ataxia.

Gee KW, Tran MB, Hogenkamp DJ, Johnstone TB, Bagnera RE, Yoshimura RF, Huang JC, Belluzzi JD, Whittemore ER. Gee KW, et al. Among authors: huang jc. J Pharmacol Exp Ther. 2010 Mar;332(3):1040-53. doi: 10.1124/jpet.109.161885. Epub 2009 Nov 25. J Pharmacol Exp Ther. 2010. PMID: 19940102 Free PMC article.

8

Molecular amplifiers: synthesis and functionalization of a poly(aminopropyl)dextran bearing a uniquely reactive terminus for univalent attachment to biomolecules.

Mann JS, Huang JC, Keana JF. Mann JS, et al. Among authors: huang jc. Bioconjug Chem. 1992 Mar-Apr;3(2):154-9. doi: 10.1021/bc00014a010. Bioconjug Chem. 1992. PMID: 1381224

9

Allosteric modulation of related ligand-gated ion channels synergistically induces long-term potentiation in the hippocampus and enhances cognition.

Johnstone TB, Gu Z, Yoshimura RF, Villegier AS, Hogenkamp DJ, Whittemore ER, Huang JC, Tran MB, Belluzzi JD, Yakel JL, Gee KW. Johnstone TB, et al. Among authors: huang jc. J Pharmacol Exp Ther. 2011 Mar;336(3):908-15. doi: 10.1124/jpet.110.176255. Epub 2010 Dec 15. J Pharmacol Exp Ther. 2011. PMID: 21159751 Free PMC article.

10

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity.

Yang W, Guastella J, Huang JC, Wang Y, Zhang L, Xue D, Tran M, Woodward R, Kasibhatla S, Tseng B, Drewe J, Cai SX. Yang W, et al. Among authors: huang jc. Br J Pharmacol. 2003 Sep;140(2):402-12. doi: 10.1038/sj.bjp.0705450. Epub 2003 Aug 26. Br J Pharmacol. 2003. PMID: 12970077 Free PMC article.

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