B cell function in mice transgenic for mCTLA4-H gamma 1: lack of germinal centers correlated with poor affinity maturation and class switching despite normal priming of CD4+ T cells.
Lane P, Burdet C, Hubele S, Scheidegger D, Müller U, McConnell F, Kosco-Vilbois M.
Lane P, et al.
J Exp Med. 1994 Mar 1;179(3):819-30. doi: 10.1084/jem.179.3.819.
J Exp Med. 1994.
PMID: 7509361
Free PMC article.
Despite the fact that these mice prime CD4+ T cells (Ronchese, F., B. Housemann, S. Hubele, and P. Lane. 1994. J. Exp. Med. 179:809), antibody responses to T-dependent antigens are severely impaired. ...
Despite the fact that these mice prime CD4+ T cells (Ronchese, F., B. Housemann, S. Hubele, and P. Lane. 1994. J. Exp. Med. 17 …