Wittinghofer A - Search Results

1

Conformational transitions in p21ras and in its complexes with the effector protein Raf-RBD and the GTPase activating protein GAP.

Geyer M, Schweins T, Herrmann C, Prisner T, Wittinghofer A, Kalbitzer HR. Geyer M, et al. Among authors: wittinghofer a. Biochemistry. 1996 Aug 13;35(32):10308-20. doi: 10.1021/bi952858k. Biochemistry. 1996. PMID: 8756686

2

Conformational states of Ras complexed with the GTP analogue GppNHp or GppCH2p: implications for the interaction with effector proteins.

Spoerner M, Nuehs A, Ganser P, Herrmann C, Wittinghofer A, Kalbitzer HR. Spoerner M, et al. Among authors: wittinghofer a. Biochemistry. 2005 Feb 15;44(6):2225-36. doi: 10.1021/bi0488000. Biochemistry. 2005. PMID: 15697248

3

Stereochemistry and lifetime of the GTP hydrolysis intermediate at the active site of elongation factor Tu from Bacillus stearothermophilus as inferred from the 17O-55Mn superhyperfine interaction.

Kalbitzer HR, Feuerstein J, Goody RS, Wittinghofer A. Kalbitzer HR, et al. Among authors: wittinghofer a. Eur J Biochem. 1990 Mar 10;188(2):355-9. doi: 10.1111/j.1432-1033.1990.tb15411.x. Eur J Biochem. 1990. PMID: 2156700 Free article.

4

Ras-effector interactions, the problem of specificity.

Wittinghofer A, Herrmann C. Wittinghofer A, et al. FEBS Lett. 1995 Aug 1;369(1):52-6. doi: 10.1016/0014-5793(95)00667-x. FEBS Lett. 1995. PMID: 7641884 Free article. Review.

5

Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins.

Schweins T, Geyer M, Scheffzek K, Warshel A, Kalbitzer HR, Wittinghofer A. Schweins T, et al. Among authors: wittinghofer a. Nat Struct Biol. 1995 Jan;2(1):36-44. doi: 10.1038/nsb0195-36. Nat Struct Biol. 1995. PMID: 7719852

6

Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase.

Herrmann C, Martin GA, Wittinghofer A. Herrmann C, et al. Among authors: wittinghofer a. J Biol Chem. 1995 Feb 17;270(7):2901-5. doi: 10.1074/jbc.270.7.2901. J Biol Chem. 1995. PMID: 7852367 Free article.

7

Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.

Schweins T, Geyer M, Kalbitzer HR, Wittinghofer A, Warshel A. Schweins T, et al. Among authors: wittinghofer a. Biochemistry. 1996 Nov 12;35(45):14225-31. doi: 10.1021/bi961118o. Biochemistry. 1996. PMID: 8916907

8

Transient kinetic studies on the interaction of Ras and the Ras-binding domain of c-Raf-1 reveal rapid equilibration of the complex.

Sydor JR, Engelhard M, Wittinghofer A, Goody RS, Herrmann C. Sydor JR, et al. Among authors: wittinghofer a. Biochemistry. 1998 Oct 6;37(40):14292-9. doi: 10.1021/bi980764f. Biochemistry. 1998. PMID: 9760267

9

Conformational states of the nuclear GTP-binding protein Ran and its complexes with the exchange factor RCC1 and the effector protein RanBP1.

Geyer M, Assheuer R, Klebe C, Kuhlmann J, Becker J, Wittinghofer A, Kalbitzer HR. Geyer M, et al. Among authors: wittinghofer a. Biochemistry. 1999 Aug 31;38(35):11250-60. doi: 10.1021/bi9904306. Biochemistry. 1999. PMID: 10471274

10

Structure of the metal-water complex in Ras x GDP studied by high-field EPR spectroscopy and 31P NMR spectroscopy.

Rohrer M, Prisner TF, Brügmann O, Käss H, Spoerner M, Wittinghofer A, Kalbitzer HR. Rohrer M, et al. Among authors: wittinghofer a. Biochemistry. 2001 Feb 20;40(7):1884-9. doi: 10.1021/bi002164y. Biochemistry. 2001. PMID: 11329253

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