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Discovery of the ROCK inhibitor netarsudil for the treatment of open-angle glaucoma.
Sturdivant JM, Royalty SM, Lin CW, Moore LA, Yingling JD, Laethem CL, Sherman B, Heintzelman GR, Kopczynski CC, deLong MA. Sturdivant JM, et al. Among authors: yingling jd. Bioorg Med Chem Lett. 2016 May 15;26(10):2475-2480. doi: 10.1016/j.bmcl.2016.03.104. Epub 2016 Apr 1. Bioorg Med Chem Lett. 2016. PMID: 27072905
Three mechanistically distinct kinase assays compared: Measurement of intrinsic ATPase activity identified the most comprehensive set of ITK inhibitors.
Kashem MA, Nelson RM, Yingling JD, Pullen SS, Prokopowicz AS 3rd, Jones JW, Wolak JP, Rogers GR, Morelock MM, Snow RJ, Homon CA, Jakes S. Kashem MA, et al. Among authors: yingling jd. J Biomol Screen. 2007 Feb;12(1):70-83. doi: 10.1177/1087057106296047. Epub 2006 Dec 8. J Biomol Screen. 2007. PMID: 17166826
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