Ator MA - Search Results

1

First examples of peptidomimetic inhibitors of interleukin-1 beta converting enzyme.

Dolle RE, Prouty CP, Prasad CV, Cook E, Saha A, Ross TM, Salvino JM, Helaszek CT, Ator MA. Dolle RE, et al. Among authors: ator ma. J Med Chem. 1996 Jun 21;39(13):2438-40. doi: 10.1021/jm9601516. J Med Chem. 1996. PMID: 8691439 No abstract available.

2

Aspartyl alpha-((1-phenyl-3-(trifluoromethyl)-pyrazol-5-yl)oxy)methyl ketones as interleukin-1 beta converting enzyme inhibitors. Significance of the P1 and P3 amido nitrogens for enzyme-peptide inhibitor binding.

Dolle RE, Singh J, Rinker J, Hoyer D, Prasad CV, Graybill TL, Salvino JM, Helaszek CT, Miller RE, Ator MA. Dolle RE, et al. Among authors: ator ma. J Med Chem. 1994 Nov 11;37(23):3863-6. doi: 10.1021/jm00049a001. J Med Chem. 1994. PMID: 7966144 No abstract available.

3

Preparation and evaluation of peptidic aspartyl hemiacetals as reversible inhibitors of interleukin-1 beta converting enzyme (ICE).

Graybill TL, Dolle RE, Helaszek CT, Miller RE, Ator MA. Graybill TL, et al. Among authors: ator ma. Int J Pept Protein Res. 1994 Aug;44(2):173-82. doi: 10.1111/j.1399-3011.1994.tb00573.x. Int J Pept Protein Res. 1994. PMID: 7982761

4

P1 aspartate-based peptide alpha-((2,6-dichlorobenzoyl)oxy)methyl ketones as potent time-dependent inhibitors of interleukin-1 beta-converting enzyme.

Dolle RE, Hoyer D, Prasad CV, Schmidt SJ, Helaszek CT, Miller RE, Ator MA. Dolle RE, et al. Among authors: ator ma. J Med Chem. 1994 Mar 4;37(5):563-4. doi: 10.1021/jm00031a003. J Med Chem. 1994. PMID: 8126694 No abstract available.

5

Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1 beta-converting enzyme inhibitor.

Dolle RE, Prasad CV, Prouty CP, Salvino JM, Awad MM, Schmidt SJ, Hoyer D, Ross TM, Graybill TL, Speier GJ, Uhl J, Miller BE, Helaszek CT, Ator MA. Dolle RE, et al. Among authors: ator ma. J Med Chem. 1997 Jun 20;40(13):1941-6. doi: 10.1021/jm9701637. J Med Chem. 1997. PMID: 9207934 No abstract available.

6

Secretion of human monocyte mature IL-1 beta: optimization of culture conditions and inhibition by ICE inhibitors.

Uhl J, Krasney P, Brophy L, Arnold R, Dolle R, Helaszek C, Miller R, Gilman S, Ator M. Uhl J, et al. Inflamm Res. 1995 Aug;44 Suppl 2:S211-2. doi: 10.1007/BF01778338. Inflamm Res. 1995. PMID: 8548404 No abstract available.

7

Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase.

Ator MA, Schmidt SJ, Adams JL, Dolle RE, Kruse LI, Frey CL, Barone JM. Ator MA, et al. J Med Chem. 1992 Jan;35(1):100-6. doi: 10.1021/jm00079a012. J Med Chem. 1992. PMID: 1732516

8

Inhibition of mature IL-1 beta production in murine macrophages and a murine model of inflammation by WIN 67694, an inhibitor of IL-1 beta converting enzyme.

Miller BE, Krasney PA, Gauvin DM, Holbrook KB, Koonz DJ, Abruzzese RV, Miller RE, Pagani KA, Dolle RE, Ator MA, et al. Miller BE, et al. Among authors: ator ma. J Immunol. 1995 Feb 1;154(3):1331-8. J Immunol. 1995. PMID: 7822802

9

Production, purification, and crystallization of human interleukin-1 beta converting enzyme derived from an Escherichia coli expression system.

Malinowski JJ, Grasberger BL, Trakshel G, Huston EE, Helaszek CT, Smallwood AM, Ator MA, Banks TM, Brake PG, Ciccarelli RB, et al. Malinowski JJ, et al. Among authors: ator ma. Protein Sci. 1995 Oct;4(10):2149-55. doi: 10.1002/pro.5560041021. Protein Sci. 1995. PMID: 8535252 Free PMC article.

10

Discovery and characterization of 6-{4-[3-(R)-2-methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, irdabisant): a potent, selective histamine H3 receptor inverse agonist.

Hudkins RL, Raddatz R, Tao M, Mathiasen JR, Aimone LD, Becknell NC, Prouty CP, Knutsen LJ, Yazdanian M, Moachon G, Ator MA, Mallamo JP, Marino MJ, Bacon ER, Williams M. Hudkins RL, et al. Among authors: ator ma. J Med Chem. 2011 Jul 14;54(13):4781-92. doi: 10.1021/jm200401v. Epub 2011 Jun 2. J Med Chem. 2011. PMID: 21634396

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