Guiles JW - Search Results

1

In vitro characterization of a novel series of platelet-derived growth factor receptor tyrosine kinase inhibitors.

Sawutz DG, Bode DC, Briggs GM, Reid JR, Canniff P, Caldwell L, Faltynek CR, Miller D, Dunn JA, de Garavilla L, Guiles JW, Weigelt C, Michne W, Treasurywala AM, Silver PJ. Sawutz DG, et al. Among authors: guiles jw. Biochem Pharmacol. 1996 Jun 28;51(12):1631-8. doi: 10.1016/0006-2952(96)00112-8. Biochem Pharmacol. 1996. PMID: 8687478

2

Novel inhibitors of potassium ion channels on human T lymphocytes.

Michne WF, Guiles JW, Treasurywala AM, Castonguay LA, Weigelt CA, Oconnor B, Volberg WA, Grant AM, Chadwick CC, Krafte DS, et al. Michne WF, et al. Among authors: guiles jw. J Med Chem. 1995 May 26;38(11):1877-83. doi: 10.1021/jm00011a007. J Med Chem. 1995. PMID: 7540207

3

WIN 17317-3: novel nonpeptide antagonist of voltage-activated K+ channels in human T lymphocytes.

Hill RJ, Grant AM, Volberg W, Rapp L, Faltynek C, Miller D, Pagani K, Baizman E, Wang S, Guiles JW, et al. Hill RJ, et al. Among authors: guiles jw. Mol Pharmacol. 1995 Jul;48(1):98-104. Mol Pharmacol. 1995. PMID: 7542739

4

Novel inhibitors of the nuclear factor of activated T cells (NFAT)-mediated transcription of beta-galactosidase: potential immunosuppressive and antiinflammatory agents.

Michne WF, Schroeder JD, Guiles JW, Treasurywala AM, Weigelt CA, Stansberry MF, McAvoy E, Shah CR, Baine Y, Sawutz DG, et al. Michne WF, et al. Among authors: guiles jw. J Med Chem. 1995 Jul 7;38(14):2557-69. doi: 10.1021/jm00014a009. J Med Chem. 1995. PMID: 7629796

5

[(Biaryloxy)alkyl]isoxazoles: picornavirus inhibitors.

Guiles JW, Diana GD, Pevear DC. Guiles JW, et al. J Med Chem. 1995 Jul 7;38(14):2780-3. doi: 10.1021/jm00014a029. J Med Chem. 1995. PMID: 7629816

6

Structures of four methyltetrazole-containing antiviral compounds in human rhinovirus serotype 14.

Giranda VL, Russo GR, Felock PJ, Bailey TR, Draper T, Aldous DJ, Guiles J, Dutko FJ, Diana GD, Pevear DC, McMillan M. Giranda VL, et al. Acta Crystallogr D Biol Crystallogr. 1995 Jul 1;51(Pt 4):496-503. doi: 10.1107/S0907444994011674. Acta Crystallogr D Biol Crystallogr. 1995. PMID: 15299836

7

Quinazolin-2-ylamino-quinazolin-4-ols as novel non-nucleoside inhibitors of bacterial DNA polymerase III.

Guiles J, Sun X, Critchley IA, Ochsner U, Tregay M, Stone K, Bertino J, Green L, Sabin R, Dean F, Dallmann HG, McHenry CS, Janjic N. Guiles J, et al. Bioorg Med Chem Lett. 2009 Feb 1;19(3):800-2. doi: 10.1016/j.bmcl.2008.12.038. Epub 2008 Dec 13. Bioorg Med Chem Lett. 2009. PMID: 19109016

8

Development of 4H-pyridopyrimidines: a class of selective bacterial protein synthesis inhibitors.

Guiles JW, Toro A, Ochsner UA, Bullard JM. Guiles JW, et al. Org Med Chem Lett. 2012 Feb 16;2(1):5. doi: 10.1186/2191-2858-2-5. Org Med Chem Lett. 2012. PMID: 22373064 Free PMC article.

9

Spectrum of activity and mode of action of REP3123, a new antibiotic to treat Clostridium difficile infections.

Critchley IA, Green LS, Young CL, Bullard JM, Evans RJ, Price M, Jarvis TC, Guiles JW, Janjic N, Ochsner UA. Critchley IA, et al. Among authors: guiles jw. J Antimicrob Chemother. 2009 May;63(5):954-63. doi: 10.1093/jac/dkp041. Epub 2009 Mar 3. J Antimicrob Chemother. 2009. PMID: 19258353

10

Antibacterial activity of REP8839, a new antibiotic for topical use.

Critchley IA, Young CL, Stone KC, Ochsner UA, Guiles J, Tarasow T, Janjic N. Critchley IA, et al. Antimicrob Agents Chemother. 2005 Oct;49(10):4247-52. doi: 10.1128/AAC.49.10.4247-4252.2005. Antimicrob Agents Chemother. 2005. PMID: 16189105 Free PMC article.

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