Saksela K - Search Results

1

Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.

Lee CH, Saksela K, Mirza UA, Chait BT, Kuriyan J. Lee CH, et al. Among authors: saksela k. Cell. 1996 Jun 14;85(6):931-42. doi: 10.1016/s0092-8674(00)81276-3. Cell. 1996. PMID: 8681387 Free article.

2

A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein.

Lee CH, Leung B, Lemmon MA, Zheng J, Cowburn D, Kuriyan J, Saksela K. Lee CH, et al. Among authors: saksela k. EMBO J. 1995 Oct 16;14(20):5006-15. doi: 10.1002/j.1460-2075.1995.tb00183.x. EMBO J. 1995. PMID: 7588629 Free PMC article.

3

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4.

Saksela K, Cheng G, Baltimore D. Saksela K, et al. EMBO J. 1995 Feb 1;14(3):484-91. doi: 10.1002/j.1460-2075.1995.tb07024.x. EMBO J. 1995. PMID: 7859737 Free PMC article.

4

SH3-Domain binding function of HIV-1 Nef is required for association with a PAK-related kinase.

Manninen A, Hiipakka M, Vihinen M, Lu W, Mayer BJ, Saksela K. Manninen A, et al. Among authors: saksela k. Virology. 1998 Oct 25;250(2):273-82. doi: 10.1006/viro.1998.9381. Virology. 1998. PMID: 9792838 Free article.

5

SH3 domains with high affinity and engineered ligand specificities targeted to HIV-1 Nef.

Hiipakka M, Poikonen K, Saksela K. Hiipakka M, et al. Among authors: saksela k. J Mol Biol. 1999 Nov 12;293(5):1097-106. doi: 10.1006/jmbi.1999.3225. J Mol Biol. 1999. PMID: 10547288

6

Inhibition of cellular functions of HIV-1 Nef by artificial SH3 domains.

Hiipakka M, Huotari P, Manninen A, Renkema GH, Saksela K. Hiipakka M, et al. Among authors: saksela k. Virology. 2001 Jul 20;286(1):152-9. doi: 10.1006/viro.2001.0973. Virology. 2001. PMID: 11448168 Free article.

7

A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors.

Antoku S, Saksela K, Rivera GM, Mayer BJ. Antoku S, et al. Among authors: saksela k. J Cell Sci. 2008 Sep 15;121(Pt 18):3071-82. doi: 10.1242/jcs.031575. J Cell Sci. 2008. PMID: 18768933 Free PMC article.

8

Conformation of the dileucine-based sorting motif in HIV-1 Nef revealed by intermolecular domain assembly.

Horenkamp FA, Breuer S, Schulte A, Lülf S, Weyand M, Saksela K, Geyer M. Horenkamp FA, et al. Among authors: saksela k. Traffic. 2011 Jul;12(7):867-77. doi: 10.1111/j.1600-0854.2011.01205.x. Epub 2011 May 5. Traffic. 2011. PMID: 21477083 Free article.

9

Capacity of simian immunodeficiency virus strain mac Nef for high-affinity Src homology 3 (SH3) binding revealed by ligand-tailored SH3 domains.

Hiipakka M, Saksela K. Hiipakka M, et al. Among authors: saksela k. J Gen Virol. 2002 Dec;83(Pt 12):3147-3152. doi: 10.1099/0022-1317-83-12-3147. J Gen Virol. 2002. PMID: 12466492

10

Single-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functions.

Bouchet J, Hérate C, Guenzel CA, Vérollet C, Järviluoma A, Mazzolini J, Rafie S, Chames P, Baty D, Saksela K, Niedergang F, Maridonneau-Parini I, Benichou S. Bouchet J, et al. Among authors: saksela k. J Virol. 2012 May;86(9):4856-67. doi: 10.1128/JVI.06329-11. Epub 2012 Feb 15. J Virol. 2012. PMID: 22345475 Free PMC article.

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