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Nitric oxide-releasing polymers containing the [N(O)NO]- group.
Smith DJ, Chakravarthy D, Pulfer S, Simmons ML, Hrabie JA, Citro ML, Saavedra JE, Davies KM, Hutsell TC, Mooradian DL, Hanson SR, Keefer LK. Smith DJ, et al. Among authors: hanson sr. J Med Chem. 1996 Mar 1;39(5):1148-56. doi: 10.1021/jm950652b. J Med Chem. 1996. PMID: 8676352
A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo.
Olivero AG, Eigenbrot C, Goldsmith R, Robarge K, Artis DR, Flygare J, Rawson T, Sutherlin DP, Kadkhodayan S, Beresini M, Elliott LO, DeGuzman GG, Banner DW, Ultsch M, Marzec U, Hanson SR, Refino C, Bunting S, Kirchhofer D. Olivero AG, et al. Among authors: hanson sr. J Biol Chem. 2005 Mar 11;280(10):9160-9. doi: 10.1074/jbc.M409068200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632123 Free article.
Factor VIIa inhibitors: chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model.
Young WB, Mordenti J, Torkelson S, Shrader WD, Kolesnikov A, Rai R, Liu L, Hu H, Leahy EM, Green MJ, Sprengeler PA, Katz BA, Yu C, Janc JW, Elrod KC, Marzec UM, Hanson SR. Young WB, et al. Among authors: hanson sr. Bioorg Med Chem Lett. 2006 Apr 1;16(7):2037-41. doi: 10.1016/j.bmcl.2005.12.059. Epub 2006 Jan 18. Bioorg Med Chem Lett. 2006. PMID: 16412633
Boundary layer drug delivery using a helical catheter.
Markou CP, Brown JE, Pursley MD, Hanson SR. Markou CP, et al. Among authors: hanson sr. J Control Release. 1998 Apr 30;53(1-3):281-8. doi: 10.1016/s0168-3659(97)00262-9. J Control Release. 1998. PMID: 9741936
200 results