Worland PJ - Search Results

1

Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells.

Carlson BA, Dubay MM, Sausville EA, Brizuela L, Worland PJ. Carlson BA, et al. Among authors: worland pj. Cancer Res. 1996 Jul 1;56(13):2973-8. Cancer Res. 1996. PMID: 8674031

2

Cell cycle arrest and growth inhibition by the protein kinase antagonist UCN-01 in human breast carcinoma cells.

Seynaeve CM, Stetler-Stevenson M, Sebers S, Kaur G, Sausville EA, Worland PJ. Seynaeve CM, et al. Among authors: worland pj. Cancer Res. 1993 May 1;53(9):2081-6. Cancer Res. 1993. PMID: 7683251

3

Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.

Losiewicz MD, Carlson BA, Kaur G, Sausville EA, Worland PJ. Losiewicz MD, et al. Among authors: worland pj. Biochem Biophys Res Commun. 1994 Jun 15;201(2):589-95. doi: 10.1006/bbrc.1994.1742. Biochem Biophys Res Commun. 1994. PMID: 8002990

4

Alteration of the phosphorylation state of p34cdc2 kinase by the flavone L86-8275 in breast carcinoma cells. Correlation with decreased H1 kinase activity.

Worland PJ, Kaur G, Stetler-Stevenson M, Sebers S, Sartor O, Sausville EA. Worland PJ, et al. Biochem Pharmacol. 1993 Nov 17;46(10):1831-40. doi: 10.1016/0006-2952(93)90590-s. Biochem Pharmacol. 1993. PMID: 8250970

5

Apoptosis in 7-hydroxystaurosporine-treated T lymphoblasts correlates with activation of cyclin-dependent kinases 1 and 2.

Wang Q, Worland PJ, Clark JL, Carlson BA, Sausville EA. Wang Q, et al. Among authors: worland pj. Cell Growth Differ. 1995 Aug;6(8):927-36. Cell Growth Differ. 1995. PMID: 8547221

6

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

Wang Q, Fan S, Eastman A, Worland PJ, Sausville EA, O'Connor PM. Wang Q, et al. Among authors: worland pj. J Natl Cancer Inst. 1996 Jul 17;88(14):956-65. doi: 10.1093/jnci/88.14.956. J Natl Cancer Inst. 1996. PMID: 8667426

7

Down-regulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol.

Carlson B, Lahusen T, Singh S, Loaiza-Perez A, Worland PJ, Pestell R, Albanese C, Sausville EA, Senderowicz AM. Carlson B, et al. Among authors: worland pj. Cancer Res. 1999 Sep 15;59(18):4634-41. Cancer Res. 1999. PMID: 10493518

8

Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275.

Kaur G, Stetler-Stevenson M, Sebers S, Worland P, Sedlacek H, Myers C, Czech J, Naik R, Sausville E. Kaur G, et al. J Natl Cancer Inst. 1992 Nov 18;84(22):1736-40. doi: 10.1093/jnci/84.22.1736. J Natl Cancer Inst. 1992. PMID: 1279187

9

Differential inhibition of protein kinase C isozymes by UCN-01, a staurosporine analogue.

Seynaeve CM, Kazanietz MG, Blumberg PM, Sausville EA, Worland PJ. Seynaeve CM, et al. Among authors: worland pj. Mol Pharmacol. 1994 Jun;45(6):1207-14. Mol Pharmacol. 1994. PMID: 8022414

10

Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

De Azevedo WF Jr, Mueller-Dieckmann HJ, Schulze-Gahmen U, Worland PJ, Sausville E, Kim SH. De Azevedo WF Jr, et al. Among authors: worland pj. Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2735-40. doi: 10.1073/pnas.93.7.2735. Proc Natl Acad Sci U S A. 1996. PMID: 8610110 Free PMC article.

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