Baker R - Search Results

1

5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole: a potent, selective antagonist at human cloned dopamine D4 receptors.

Rowley M, Broughton HB, Collins I, Baker R, Emms F, Marwood R, Patel S, Patel S, Ragan CI, Freedman SB, Leeson PD. Rowley M, et al. Among authors: baker r. J Med Chem. 1996 May 10;39(10):1943-5. doi: 10.1021/jm960072u. J Med Chem. 1996. PMID: 8642551 No abstract available.

2

3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.

Kulagowski JJ, Broughton HB, Curtis NR, Mawer IM, Ridgill MP, Baker R, Emms F, Freedman SB, Marwood R, Patel S, Patel S, Ragan CI, Leeson PD. Kulagowski JJ, et al. Among authors: baker r. J Med Chem. 1996 May 10;39(10):1941-2. doi: 10.1021/jm9600712. J Med Chem. 1996. PMID: 8642550 No abstract available.

3

4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor.

Rowley M, Collins I, Broughton HB, Davey WB, Baker R, Emms F, Marwood R, Patel S, Patel S, Ragan CI, Freedman SB, Ball R, Leeson PD. Rowley M, et al. Among authors: baker r. J Med Chem. 1997 Jul 18;40(15):2374-85. doi: 10.1021/jm970111h. J Med Chem. 1997. PMID: 9240352

4

N-Arylsulfonylindole derivatives as serotonin 5-HT(6) receptor ligands.

Russell MG, Baker RJ, Barden L, Beer MS, Bristow L, Broughton HB, Knowles M, McAllister G, Patel S, Castro JL. Russell MG, et al. Among authors: baker rj. J Med Chem. 2001 Nov 8;44(23):3881-95. doi: 10.1021/jm010943m. J Med Chem. 2001. PMID: 11689074

5

2-Carboxytetrahydroquinolines. Conformational and stereochemical requirements for antagonism of the glycine site on the NMDA receptor.

Carling RW, Leeson PD, Moseley AM, Baker R, Foster AC, Grimwood S, Kemp JA, Marshall GR. Carling RW, et al. Among authors: baker r. J Med Chem. 1992 May 29;35(11):1942-53. doi: 10.1021/jm00089a003. J Med Chem. 1992. PMID: 1534583

6

4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor.

Leeson PD, Carling RW, Moore KW, Moseley AM, Smith JD, Stevenson G, Chan T, Baker R, Foster AC, Grimwood S, et al. Leeson PD, et al. Among authors: baker r. J Med Chem. 1992 May 29;35(11):1954-68. doi: 10.1021/jm00089a004. J Med Chem. 1992. PMID: 1534584

7

Synthesis and in vitro biological profile of all four isomers of the potent muscarinic agonist 3-(3-methyl-1,2,4-oxadiazol-5-yl)-1-azabicyclo[2.2.1]heptane.

Showell GA, Baker R, Davis J, Hargreaves R, Freedman SB, Hoogsteen K, Patel S, Snow RJ. Showell GA, et al. Among authors: baker r. J Med Chem. 1992 Mar 6;35(5):911-6. doi: 10.1021/jm00083a016. J Med Chem. 1992. PMID: 1548680

8

Role of hydrogen bonding in ligand interaction with the N-methyl-D-aspartate receptor ion channel.

Leeson PD, Carling RW, James K, Smith JD, Moore KW, Wong EH, Baker R. Leeson PD, et al. Among authors: baker r. J Med Chem. 1990 May;33(5):1296-305. doi: 10.1021/jm00167a005. J Med Chem. 1990. PMID: 1691788

9

Synthesis and muscarinic activity of quinuclidinyl- and (1-azanorbornyl)pyrazine derivatives.

Street LJ, Baker R, Book T, Reeve AJ, Saunders J, Willson T, Marwood RS, Patel S, Freedman SB. Street LJ, et al. Among authors: baker r. J Med Chem. 1992 Jan 24;35(2):295-305. doi: 10.1021/jm00080a014. J Med Chem. 1992. PMID: 1732546

10

Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor.

Leeson PD, Baker R, Carling RW, Curtis NR, Moore KW, Williams BJ, Foster AC, Donald AE, Kemp JA, Marshall GR. Leeson PD, et al. Among authors: baker r. J Med Chem. 1991 Apr;34(4):1243-52. doi: 10.1021/jm00108a002. J Med Chem. 1991. PMID: 1826744

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