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Deletion of the vpu sequences prior to the env in a simian-human immunodeficiency virus results in enhanced Env precursor synthesis but is less pathogenic for pig-tailed macaques.
Stephens EB, McCormick C, Pacyniak E, Griffin D, Pinson DM, Sun F, Nothnick W, Wong SW, Gunderson R, Berman NE, Singh DK. Stephens EB, et al. Among authors: pinson dm. Virology. 2002 Feb 15;293(2):252-61. doi: 10.1006/viro.2001.1244. Virology. 2002. PMID: 11886245 Free article.
The presence of the casein kinase II phosphorylation sites of Vpu enhances the CD4(+) T cell loss caused by the simian-human immunodeficiency virus SHIV(KU-lbMC33) in pig-tailed macaques.
Singh DK, Griffin DM, Pacyniak E, Jackson M, Werle MJ, Wisdom B, Sun F, Hout DR, Pinson DM, Gunderson RS, Powers MF, Wong SW, Stephens EB. Singh DK, et al. Among authors: pinson dm. Virology. 2003 Sep 1;313(2):435-51. doi: 10.1016/s0042-6822(03)00339-8. Virology. 2003. PMID: 12954211 Free article.
Fusion of the upstream vpu sequences to the env of simian human immunodeficiency virus (SHIV(KU-1bMC33)) results in the synthesis of two envelope precursor proteins, increased numbers of virus particles associated with the cell surface and is pathogenic for pig-tailed macaques.
Hout DR, Gomez ML, Pacyniak E, Mulcahy ER, Gomez LM, Jackson M, Flick M, Fegley B, McCormick C, Wisdom BJ, Culley N, Pinson DM, Powers M, Wong SW, Stephens EB. Hout DR, et al. Among authors: pinson dm. Virology. 2004 May 20;323(1):91-107. doi: 10.1016/j.virol.2004.02.028. Virology. 2004. PMID: 15165822 Free article.
102 results