Smith RG - Search Results

1

Development of a high specific activity sulfur-35-labeled sulfonamide radioligand that allowed the identification of a new growth hormone secretagogue receptor.

Dean DC, Nargund RP, Pong SS, Chaung LY, Griffin P, Melillo DG, Ellsworth RL, Van der Ploeg LH, Patchett AA, Smith RG. Dean DC, et al. Among authors: smith rg. J Med Chem. 1996 Apr 26;39(9):1767-70. doi: 10.1021/jm960054c. J Med Chem. 1996. PMID: 8627599 No abstract available.

2

A receptor in pituitary and hypothalamus that functions in growth hormone release.

Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, Hamelin M, Hreniuk DL, Palyha OC, Anderson J, Paress PS, Diaz C, Chou M, Liu KK, McKee KK, Pong SS, Chaung LY, Elbrecht A, Dashkevicz M, Heavens R, Rigby M, Sirinathsinghji DJ, Dean DC, Melillo DG, Patchett AA, Nargund R, Griffin PR, DeMartino JA, Gupta SK, Schaeffer JM, Smith RG, Van der Ploeg LH. Howard AD, et al. Among authors: smith rg. Science. 1996 Aug 16;273(5277):974-7. doi: 10.1126/science.273.5277.974. Science. 1996. PMID: 8688086

3

Identification of a new G-protein-linked receptor for growth hormone secretagogues.

Pong SS, Chaung LY, Dean DC, Nargund RP, Patchett AA, Smith RG. Pong SS, et al. Among authors: smith rg. Mol Endocrinol. 1996 Jan;10(1):57-61. doi: 10.1210/mend.10.1.8838145. Mol Endocrinol. 1996. PMID: 8838145

4

Peptidomimetic growth hormone secretagogues. Design considerations and therapeutic potential.

Nargund RP, Patchett AA, Bach MA, Murphy MG, Smith RG. Nargund RP, et al. Among authors: smith rg. J Med Chem. 1998 Aug 13;41(17):3103-27. doi: 10.1021/jm970342o. J Med Chem. 1998. PMID: 9703459 Review. No abstract available.

5

Tripeptide growth hormone secretagogues.

Yang L, Morriello G, Pan Y, Nargund RP, Barakat K, Prendergast K, Cheng K, Chan WW, Smith RG, Patchett AA. Yang L, et al. Among authors: smith rg. Bioorg Med Chem Lett. 1998 Apr 7;8(7):759-64. doi: 10.1016/s0960-894x(98)00103-6. Bioorg Med Chem Lett. 1998. PMID: 9871537

6

Synthesis and biological activities of phenyl piperazine-based peptidomimetic growth hormone secretagogues.

Barakat KJ, Cheng K, Chan WW, Butler BS, Jacks TM, Schleim KD, Hora DF Jr, Hickey GJ, Smith RG, Patchett AA, Nargund RP. Barakat KJ, et al. Among authors: smith rg. Bioorg Med Chem Lett. 1998 Jun 2;8(11):1431-6. doi: 10.1016/s0960-894x(98)00238-8. Bioorg Med Chem Lett. 1998. PMID: 9871779

7

Synthesis and biological activities of spiroheterocyclic growth hormone secretagogues.

Chen MH, Pollard PP, Patchett AA, Cheng K, Wei L, Chan WW, Butler B, Jacks TM, Smith RG. Chen MH, et al. Among authors: smith rg. Bioorg Med Chem Lett. 1999 May 3;9(9):1261-6. doi: 10.1016/s0960-894x(99)00183-3. Bioorg Med Chem Lett. 1999. PMID: 10340611

8

Potent 3-spiropiperidine growth hormone secretagogues.

Yang L, Morriello G, Prendergast K, Cheng K, Jacks T, Chan WW, Schleim KD, Smith RG, Patchett AA. Yang L, et al. Among authors: smith rg. Bioorg Med Chem Lett. 1998 Jan 6;8(1):107-12. doi: 10.1016/s0960-894x(97)10199-8. Bioorg Med Chem Lett. 1998. PMID: 9925440

9

MK-0677, a potent, novel, orally active growth hormone (GH) secretagogue: GH, insulin-like growth factor I, and other hormonal responses in beagles.

Jacks T, Smith R, Judith F, Schleim K, Frazier E, Chen H, Krupa D, Hora D Jr, Nargund R, Patchett A, Hickey G. Jacks T, et al. Endocrinology. 1996 Dec;137(12):5284-9. doi: 10.1210/endo.137.12.8940347. Endocrinology. 1996. PMID: 8940347

10

Thiazole-derived potent, highly bioavailable short duration growth hormone secretagogues.

Yang L, Morriello G, Leung K, Jacks T, Cheng K, Schleim KD, Smith R, Patchett AA. Yang L, et al. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1761-6. doi: 10.1016/s0960-894x(99)00286-3. Bioorg Med Chem Lett. 1999. PMID: 10406638

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