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A common requirement for the catalytic activity and both SH2 domains of SHP-2 in mitogen-activated protein (MAP) kinase activation by the ErbB family of receptors. A specific role for SHP-2 in map, but not c-Jun amino-terminal kinase activation.
Deb TB, Wong L, Salomon DS, Zhou G, Dixon JE, Gutkind JS, Thompson SA, Johnson GR. Deb TB, et al. Among authors: zhou g. J Biol Chem. 1998 Jul 3;273(27):16643-6. doi: 10.1074/jbc.273.27.16643. J Biol Chem. 1998. PMID: 9642214 Free article.
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