Handa M - Search Results

1

Protein tyrosine phosphorylation in human platelets during shear stress-induced platelet aggregation (SIPA) is regulated by glycoprotein (GP) Ib/IX as well as GP IIb/IIIa and requires intact cytoskeleton and endogenous ADP.

Oda A, Yokoyama K, Murata M, Tokuhira M, Nakamura K, Handa M, Watanabe K, Ikeda Y. Oda A, et al. Among authors: handa m. Thromb Haemost. 1995 Aug;74(2):736-42. Thromb Haemost. 1995. PMID: 8585015

2

A novel polymorphism, 70Leu/Phe, disrupts a consensus Leu residue within the leucine-rich repeat sequence of platelet glycoprotein Ibalpha.

Matsubara Y, Murata M, Moriki T, Yokoyama K, Watanabe N, Nakajima H, Handa M, Kawano K, Aoki N, Yoshino H, Ikeda Y. Matsubara Y, et al. Among authors: handa m. Thromb Haemost. 2002 May;87(5):867-72. Thromb Haemost. 2002. PMID: 12038791

3

Bernard-soulier syndrome with a homozygous 13 base pair deletion in the signal peptide-coding region of the platelet glycoprotein Ib(beta) gene.

Watanabe R, Ishibashi T, Saitoh Y, Shichishima T, Maruyama Y, Enomoto Y, Handa M, Oda A, Ambo H, Murata M, Ikeda Y. Watanabe R, et al. Among authors: handa m. Blood Coagul Fibrinolysis. 2003 Jun;14(4):387-94. doi: 10.1097/00001721-200306000-00010. Blood Coagul Fibrinolysis. 2003. PMID: 12945881

4

Enhancing effect by heparin on shear-induced platelet aggregation.

Kawano K, Ikeda Y, Handa M, Kamata T, Anbo H, Araki Y, Kawai Y, Watanabe K, Itagaki I, Kawakami K, et al. Kawano K, et al. Among authors: handa m. Semin Thromb Hemost. 1990 Oct;16 Suppl:60-5. Semin Thromb Hemost. 1990. PMID: 1962907

5

Continuous measurement of shear-induced platelet aggregation.

Fukuyama M, Sakai K, Itagaki I, Kawano K, Murata M, Kawai Y, Watanabe K, Handa M, Ikeda Y. Fukuyama M, et al. Among authors: handa m. Thromb Res. 1989 May 1;54(3):253-60. doi: 10.1016/0049-3848(89)90233-8. Thromb Res. 1989. PMID: 2501904

6

Platelet unresponsiveness to collagen: involvement of glycoprotein Ia-IIa (alpha 2 beta 1 integrin) deficiency associated with a myeloproliferative disorder.

Handa M, Watanabe K, Kawai Y, Kamata T, Koyama T, Nagai H, Ikeda Y. Handa M, et al. Thromb Haemost. 1995 Mar;73(3):521-8. Thromb Haemost. 1995. PMID: 7667837

7

Recombinant thrombopoietin induces rapid protein tyrosine phosphorylation of Janus kinase 2 and Shc in human blood platelets.

Miyakawa Y, Oda A, Druker BJ, Kato T, Miyazaki H, Handa M, Ikeda Y. Miyakawa Y, et al. Among authors: handa m. Blood. 1995 Jul 1;86(1):23-7. Blood. 1995. PMID: 7795229 Free article.

8

Low shear stress can initiate von Willebrand factor-dependent platelet aggregation in patients with type IIB and platelet-type von Willebrand disease.

Murata M, Fukuyama M, Satoh K, Fujimura Y, Yoshioka A, Takahashi H, Handa M, Kawai Y, Watanabe K, Ikeda Y. Murata M, et al. Among authors: handa m. J Clin Invest. 1993 Sep;92(3):1555-8. doi: 10.1172/JCI116735. J Clin Invest. 1993. PMID: 8376606 Free PMC article.

Using a modified cone and plate type viscometer, we previously demonstrated that, under low shear stress (18 dyn/cm2), aggregation is mediated by platelet membrane glycoprotein (GP) IIb-IIIa and fibrinogen, whereas aggregation induced by high shear stress (108 dyn/cm2) requires t …

Using a modified cone and plate type viscometer, we previously demonstrated that, under low shear stress (18 dyn/cm2), aggregation is mediat …

9

Transmembrane calcium influx associated with von Willebrand factor binding to GP Ib in the initiation of shear-induced platelet aggregation.

Ikeda Y, Handa M, Kamata T, Kawano K, Kawai Y, Watanabe K, Kawakami K, Sakai K, Fukuyama M, Itagaki I, et al. Ikeda Y, et al. Among authors: handa m. Thromb Haemost. 1993 May 3;69(5):496-502. Thromb Haemost. 1993. PMID: 8391728

10

Thrombopoietin induces tyrosine phosphorylation of Stat3 and Stat5 in human blood platelets.

Miyakawa Y, Oda A, Druker BJ, Miyazaki H, Handa M, Ohashi H, Ikeda Y. Miyakawa Y, et al. Among authors: handa m. Blood. 1996 Jan 15;87(2):439-46. Blood. 1996. PMID: 8555464 Free article. Review.

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