Kohn LD - Search Results

1

Molecular studies on thyrotropin (TSH) receptor and anti-TSH receptor antibodies.

Akamizu T, Kohn LD, Mori T. Akamizu T, et al. Among authors: kohn ld. Endocr J. 1995 Oct;42(5):617-27. doi: 10.1507/endocrj.42.617. Endocr J. 1995. PMID: 8574284 Free article. Review.

2

[Anti-thyrotropin (TSH) receptor antibody binding epitopes of TSH receptor: site-directed mutagenesis approach].

Akamizu T, Kosugi S, Kohn LD, Mori T. Akamizu T, et al. Among authors: kohn ld. Nihon Rinsho. 1994 Apr;52(4):1024-30. Nihon Rinsho. 1994. PMID: 7515117 Review. Japanese.

3

The middle portion in the second cytoplasmic loop of the thyrotropin receptor plays a crucial role in adenylate cyclase activation.

Kosugi S, Kohn LD, Akamizu T, Mori T. Kosugi S, et al. Among authors: kohn ld. Mol Endocrinol. 1994 Apr;8(4):498-509. doi: 10.1210/mend.8.4.7914349. Mol Endocrinol. 1994. PMID: 7914349

4

Chimeric studies of the extracellular domain of the rat thyrotropin (TSH) receptor: amino acids (268-304) in the TSH receptor are involved in ligand high affinity binding, but not in TSH receptor-specific signal transduction.

Akamizu T, Inoue D, Kosugi S, Ban T, Kohn LD, Imura H, Mori T. Akamizu T, et al. Among authors: kohn ld. Endocr J. 1993 Jun;40(3):363-72. doi: 10.1507/endocrj.40.363. Endocr J. 1993. PMID: 7920890 Free article.

5

Further studies of amino acids (268-304) in thyrotropin (TSH)--lutropin/chorionic gonadotropin (LH/CG) receptor chimeras: cysteine-301 is important in TSH binding and receptor tertiary structure.

Akamizu T, Inoue D, Kosugi S, Kohn LD, Mori T. Akamizu T, et al. Among authors: kohn ld. Thyroid. 1994 Spring;4(1):43-8. doi: 10.1089/thy.1994.4.43. Thyroid. 1994. PMID: 8054860

6

Hashimoto's thyroiditis with heterogeneous antithyrotropin receptor antibodies: unique epitopes may contribute to the regulation of thyroid function by the antibodies.

Akamizu T, Kohn LD, Hiratani H, Saijo M, Tahara K, Nakao K. Akamizu T, et al. Among authors: kohn ld. J Clin Endocrinol Metab. 2000 Jun;85(6):2116-21. doi: 10.1210/jcem.85.6.6639. J Clin Endocrinol Metab. 2000. PMID: 10852437

7

Characterization of the 5'-flanking region of the rat thyrotropin receptor gene.

Ikuyama S, Niller HH, Shimura H, Akamizu T, Kohn LD. Ikuyama S, et al. Among authors: kohn ld. Mol Endocrinol. 1992 May;6(5):793-804. doi: 10.1210/mend.6.5.1318504. Mol Endocrinol. 1992. PMID: 1318504

8

Opposite regulation of deoxyribonucleic acid synthesis and iodide uptake in rat thyroid cells by basic fibroblast growth factor: correlation with opposite regulation of c-fos and thyrotropin receptor gene expression.

Isozaki O, Emoto N, Tsushima T, Sato Y, Shizume K, Demura H, Akamizu T, Kohn LD. Isozaki O, et al. Among authors: kohn ld. Endocrinology. 1992 Dec;131(6):2723-32. doi: 10.1210/endo.131.6.1332847. Endocrinology. 1992. PMID: 1332847

9

Role of cysteine residues in the extracellular domain and exoplasmic loops of the transmembrane domain of the TSH receptor: effect of mutation to serine on TSH receptor activity and response to thyroid stimulating autoantibodies.

Kosugi S, Ban T, Akamizu T, Kohn LD. Kosugi S, et al. Among authors: kohn ld. Biochem Biophys Res Commun. 1992 Dec 30;189(3):1754-62. doi: 10.1016/0006-291x(92)90281-o. Biochem Biophys Res Commun. 1992. PMID: 1336379

10

Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid-stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxedema: these determinants have no homologous sequence on gonadotropin receptors.

Kosugi S, Ban T, Akamizu T, Kohn LD. Kosugi S, et al. Among authors: kohn ld. Mol Endocrinol. 1992 Feb;6(2):168-80. doi: 10.1210/mend.6.2.1349156. Mol Endocrinol. 1992. PMID: 1349156

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