Lennard L - Search Results

1

Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism.

Szumlanski C, Otterness D, Her C, Lee D, Brandriff B, Kelsell D, Spurr N, Lennard L, Wieben E, Weinshilboum R. Szumlanski C, et al. Among authors: lennard l. DNA Cell Biol. 1996 Jan;15(1):17-30. doi: 10.1089/dna.1996.15.17. DNA Cell Biol. 1996. PMID: 8561894

2

Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms.

Otterness D, Szumlanski C, Lennard L, Klemetsdal B, Aarbakke J, Park-Hah JO, Iven H, Schmiegelow K, Branum E, O'Brien J, Weinshilboum R. Otterness D, et al. Among authors: lennard l. Clin Pharmacol Ther. 1997 Jul;62(1):60-73. doi: 10.1016/S0009-9236(97)90152-1. Clin Pharmacol Ther. 1997. PMID: 9246020

3

Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism.

Lennard L, Van Loon JA, Weinshilboum RM. Lennard L, et al. Clin Pharmacol Ther. 1989 Aug;46(2):149-54. doi: 10.1038/clpt.1989.119. Clin Pharmacol Ther. 1989. PMID: 2758725

4

Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia.

Lennard L, Lilleyman JS, Van Loon J, Weinshilboum RM. Lennard L, et al. Lancet. 1990 Jul 28;336(8709):225-9. doi: 10.1016/0140-6736(90)91745-v. Lancet. 1990. PMID: 1973780

5

Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations.

Lennard L, Van Loon JA, Lilleyman JS, Weinshilboum RM. Lennard L, et al. Clin Pharmacol Ther. 1987 Jan;41(1):18-25. doi: 10.1038/clpt.1987.4. Clin Pharmacol Ther. 1987. PMID: 3467886

6

Olsalazine and 6-mercaptopurine-related bone marrow suppression: a possible drug-drug interaction.

Lewis LD, Benin A, Szumlanski CL, Otterness DM, Lennard L, Weinshilboum RM, Nierenberg DW. Lewis LD, et al. Among authors: lennard l. Clin Pharmacol Ther. 1997 Oct;62(4):464-75. doi: 10.1016/S0009-9236(97)90125-9. Clin Pharmacol Ther. 1997. PMID: 9357398

7

Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes.

Matimba A, Li F, Livshits A, Cartwright CS, Scully S, Fridley BL, Jenkins G, Batzler A, Wang L, Weinshilboum R, Lennard L. Matimba A, et al. Among authors: lennard l. Pharmacogenomics. 2014 Mar;15(4):433-47. doi: 10.2217/pgs.13.226. Pharmacogenomics. 2014. PMID: 24624911 Free PMC article. Clinical Trial.

8

Nomenclature for alleles of the thiopurine methyltransferase gene.

Appell ML, Berg J, Duley J, Evans WE, Kennedy MA, Lennard L, Marinaki T, McLeod HL, Relling MV, Schaeffeler E, Schwab M, Weinshilboum R, Yeoh AE, McDonagh EM, Hebert JM, Klein TE, Coulthard SA. Appell ML, et al. Among authors: lennard l. Pharmacogenet Genomics. 2013 Apr;23(4):242-8. doi: 10.1097/FPC.0b013e32835f1cc0. Pharmacogenet Genomics. 2013. PMID: 23407052 Free PMC article.

9

Individualizing therapy with 6-mercaptopurine and 6-thioguanine related to the thiopurine methyltransferase genetic polymorphism.

Lennard L, Lilleyman JS. Lennard L, et al. Ther Drug Monit. 1996 Aug;18(4):328-34. doi: 10.1097/00007691-199608000-00003. Ther Drug Monit. 1996. PMID: 8857546

10

The thiopurine methyltransferase genetic polymorphism is associated with thioguanine-related veno-occlusive disease of the liver in children with acute lymphoblastic leukemia.

Lennard L, Richards S, Cartwright CS, Mitchell C, Lilleyman JS, Vora A; UK MRC/NCRI Childhood Leukaemia Working Party. Lennard L, et al. Clin Pharmacol Ther. 2006 Oct;80(4):375-83. doi: 10.1016/j.clpt.2006.07.002. Clin Pharmacol Ther. 2006. PMID: 17015055 Clinical Trial.

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