Pratt WB - Search Results

1

Differential effects of the reversible thiol-reactive agents arsenite and methyl methanethiosulfonate on steroid binding by the glucocorticoid receptor.

Stancato LF, Hutchison KA, Chakraborti PK, Simons SS Jr, Pratt WB. Stancato LF, et al. Among authors: pratt wb. Biochemistry. 1993 Apr 13;32(14):3729-36. doi: 10.1021/bi00065a027. Biochemistry. 1993. PMID: 8466913

2

Selective molybdate-directed covalent modification of sulfhydryl groups in the steroid-binding versus the DNA-binding domain of the glucocorticoid receptor.

Meshinchi S, Matić G, Hutchison KA, Pratt WB. Meshinchi S, et al. Among authors: pratt wb. J Biol Chem. 1990 Jul 15;265(20):11643-9. J Biol Chem. 1990. PMID: 2365690 Free article.

3

The 23-kDa acidic protein in reticulocyte lysate is the weakly bound component of the hsp foldosome that is required for assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90.

Hutchison KA, Stancato LF, Owens-Grillo JK, Johnson JL, Krishna P, Toft DO, Pratt WB. Hutchison KA, et al. Among authors: pratt wb. J Biol Chem. 1995 Aug 11;270(32):18841-7. doi: 10.1074/jbc.270.32.18841. J Biol Chem. 1995. PMID: 7642537 Free article.

4

The cyclosporin A-binding immunophilin CyP-40 and the FK506-binding immunophilin hsp56 bind to a common site on hsp90 and exist in independent cytosolic heterocomplexes with the untransformed glucocorticoid receptor.

Owens-Grillo JK, Hoffmann K, Hutchison KA, Yem AW, Deibel MR Jr, Handschumacher RE, Pratt WB. Owens-Grillo JK, et al. Among authors: pratt wb. J Biol Chem. 1995 Sep 1;270(35):20479-84. doi: 10.1074/jbc.270.35.20479. J Biol Chem. 1995. PMID: 7657624 Free article.

5

FK506 binding to the 56-kilodalton immunophilin (Hsp56) in the glucocorticoid receptor heterocomplex has no effect on receptor folding or function.

Hutchison KA, Scherrer LC, Czar MJ, Ning Y, Sanchez ER, Leach KL, Deibel MR Jr, Pratt WB. Hutchison KA, et al. Among authors: pratt wb. Biochemistry. 1993 Apr 20;32(15):3953-7. doi: 10.1021/bi00066a015. Biochemistry. 1993. PMID: 7682438

6

All of the factors required for assembly of the glucocorticoid receptor into a functional heterocomplex with heat shock protein 90 are preassociated in a self-sufficient protein folding structure, a "foldosome".

Hutchison KA, Dittmar KD, Pratt WB. Hutchison KA, et al. Among authors: pratt wb. J Biol Chem. 1994 Nov 11;269(45):27894-9. J Biol Chem. 1994. PMID: 7961721 Free article.

7

Proof that hsp70 is required for assembly of the glucocorticoid receptor into a heterocomplex with hsp90.

Hutchison KA, Dittmar KD, Czar MJ, Pratt WB. Hutchison KA, et al. Among authors: pratt wb. J Biol Chem. 1994 Feb 18;269(7):5043-9. J Biol Chem. 1994. PMID: 8106480 Free article.

8

Localization of the approximately 12 kDa M(r) discrepancy in gel migration of the mouse glucocorticoid receptor to the major phosphorylated cyanogen bromide fragment in the transactivating domain.

Hutchison KA, Dalman FC, Hoeck W, Groner B, Pratt WB. Hutchison KA, et al. Among authors: pratt wb. J Steroid Biochem Mol Biol. 1993 Dec;46(6):681-6. doi: 10.1016/0960-0760(93)90309-k. J Steroid Biochem Mol Biol. 1993. PMID: 8274402 Free article.

9

Regulation of glucocorticoid receptor function through assembly of a receptor-heat shock protein complex.

Hutchison KA, Scherrer LC, Czar MJ, Stancato LF, Chow YH, Jove R, Pratt WB. Hutchison KA, et al. Among authors: pratt wb. Ann N Y Acad Sci. 1993 Jun 11;684:35-48. doi: 10.1111/j.1749-6632.1993.tb32269.x. Ann N Y Acad Sci. 1993. PMID: 8317846 Free article. Review.

10

Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90.

Scherrer LC, Picard D, Massa E, Harmon JM, Simons SS Jr, Yamamoto KR, Pratt WB. Scherrer LC, et al. Among authors: pratt wb. Biochemistry. 1993 May 25;32(20):5381-6. doi: 10.1021/bi00071a013. Biochemistry. 1993. PMID: 8499442

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