Sein JJ - Search Results

1

A phase I study of prolonged continuous infusion of low dose recombinant interleukin-2 in melanoma and renal cell cancer. Part II: Immunological aspects.

Vlasveld LT, Hekman A, Vyth-Dreese FA, Rankin EM, Scharenberg JG, Voordouw AC, Sein JJ, Dellemijn TA, Rodenhuis S, Melief CJ. Vlasveld LT, et al. Among authors: sein jj. Br J Cancer. 1993 Sep;68(3):559-67. doi: 10.1038/bjc.1993.386. Br J Cancer. 1993. PMID: 8353046 Free PMC article. Clinical Trial.

2

Phase I trial of combined immunotherapy with subcutaneous granulocyte macrophage colony-stimulating factor, low-dose interleukin 2, and interferon alpha in progressive metastatic melanoma and renal cell carcinoma.

de Gast GC, Klümpen HJ, Vyth-Dreese FA, Kersten MJ, Verra NC, Sein J, Batchelor D, Nooijen WJ, Schornagel JH. de Gast GC, et al. Clin Cancer Res. 2000 Apr;6(4):1267-72. Clin Cancer Res. 2000. PMID: 10778950 Clinical Trial.

3

Temozolomide followed by combined immunotherapy with GM-CSF, low-dose IL2 and IFN alpha in patients with metastatic melanoma.

de Gast GC, Batchelor D, Kersten MJ, Vyth-Dreese FA, Sein J, van de Kasteele WF, Nooijen WJ, Nieweg OE, de Waal MA, Boogerd W. de Gast GC, et al. Br J Cancer. 2003 Jan 27;88(2):175-80. doi: 10.1038/sj.bjc.6600717. Br J Cancer. 2003. PMID: 12610499 Free PMC article.

4

Immunotherapy with concurrent subcutaneous GM-CSF, low-dose IL-2 and IFN-alpha in patients with progressive metastatic renal cell carcinoma.

Verra N, Jansen R, Groenewegen G, Mallo H, Kersten MJ, Bex A, Vyth-Dreese FA, Sein J, van de Kasteele W, Nooijen WJ, de Waal M, Horenblas S, de Gast GC. Verra N, et al. Br J Cancer. 2003 May 6;88(9):1346-51. doi: 10.1038/sj.bjc.6600915. Br J Cancer. 2003. PMID: 12778059 Free PMC article. Clinical Trial.

5

Treatment of low-grade non-Hodgkin's lymphoma with continuous infusion of low-dose recombinant interleukin-2 in combination with the B-cell-specific monoclonal antibody CLB-CD19.

Vlasveld LT, Hekman A, Vyth-Dreese FA, Melief CJ, Sein JJ, Voordouw AC, Dellemijn TA, Rankin EM. Vlasveld LT, et al. Among authors: sein jj. Cancer Immunol Immunother. 1995 Jan;40(1):37-47. doi: 10.1007/BF01517234. Cancer Immunol Immunother. 1995. PMID: 7530170 Free PMC article. Clinical Trial.

6

Enhanced antitumor effects of CD20 over CD19 monoclonal antibodies in a nude mouse xenograft model.

Hooijberg E, van den Berk PC, Sein JJ, Wijdenes J, Hart AA, de Boer RW, Melief CJ, Hekman A. Hooijberg E, et al. Among authors: sein jj. Cancer Res. 1995 Feb 15;55(4):840-6. Cancer Res. 1995. PMID: 7531616

7

Eradication of large human B cell tumors in nude mice with unconjugated CD20 monoclonal antibodies and interleukin 2.

Hooijberg E, Sein JJ, van den Berk PC, Hart AA, van der Valk MA, Kast WM, Melief CJ, Hekman A. Hooijberg E, et al. Among authors: sein jj. Cancer Res. 1995 Jun 15;55(12):2627-34. Cancer Res. 1995. PMID: 7540106

8

Reconstitution of recombinant interleukin-2 (rIL-2): a comparative study of various rIL-2 muteins.

Vlasveld LT, Beijnen JH, Sein JJ, Rankin EM, Melief CJ, Hekman A. Vlasveld LT, et al. Among authors: sein jj. Eur J Cancer. 1993;29A(14):1977-9. doi: 10.1016/0959-8049(93)90456-p. Eur J Cancer. 1993. PMID: 8280492

9

Possible role for cytotoxic lymphocytes in the pathogenesis of acute interstitial nephritis after recombinant interleukin-2 treatment for renal cell cancer.

Vlasveld LT, van de Wiel-van Kemenade E, de Boer AJ, Sein JJ, Gallee MP, Krediet RT, Mellief CJ, Rankin EM, Hekman A, Figdor CG. Vlasveld LT, et al. Among authors: sein jj. Cancer Immunol Immunother. 1993;36(3):210-3. doi: 10.1007/BF01741094. Cancer Immunol Immunother. 1993. PMID: 8439983 Free PMC article.

10

Initial experience with treatment of human B cell lymphoma with anti-CD19 monoclonal antibody.

Hekman A, Honselaar A, Vuist WM, Sein JJ, Rodenhuis S, ten Bokkel Huinink WW, Somers R, Rümke P, Melief CJ. Hekman A, et al. Among authors: sein jj. Cancer Immunol Immunother. 1991;32(6):364-72. doi: 10.1007/BF01741331. Cancer Immunol Immunother. 1991. PMID: 1706642 Free PMC article. Clinical Trial.

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