Novak PM - Search Results

1

Synthesis and pharmacological evaluation of 4a-phenanthrenamine derivatives acting at the phencyclidine binding site of the N-methyl-D-aspartate receptor complex.

Bigge CF, Malone TC, Hays SJ, Johnson G, Novak PM, Lescosky LJ, Retz DM, Ortwine DF, Probert AW Jr, Coughenour LL, et al. Bigge CF, et al. Among authors: novak pm. J Med Chem. 1993 Jul 9;36(14):1977-95. doi: 10.1021/jm00066a007. J Med Chem. 1993. PMID: 8336337

2

New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure-activity relationships and pharmacological evaluation.

Hays SJ, Bigge CF, Novak PM, Drummond JT, Bobovski TP, Rice MJ, Johnson G, Brahce LJ, Coughenour LL. Hays SJ, et al. Among authors: novak pm. J Med Chem. 1990 Oct;33(10):2916-24. doi: 10.1021/jm00172a037. J Med Chem. 1990. PMID: 2145436

3

Synthesis and pharmacological evaluation of hexahydrofluorenamines as noncompetitive antagonists at the N-methyl-D-aspartate receptor.

Hays SJ, Novak PM, Ortwine DF, Bigge CF, Colbry NL, Johnson G, Lescosky LJ, Malone TC, Michael A, Reily MD, et al. Hays SJ, et al. Among authors: novak pm. J Med Chem. 1993 Mar 19;36(6):654-70. doi: 10.1021/jm00058a002. J Med Chem. 1993. PMID: 8459395

4

Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-Kit.

Hu E, Tasker A, White RD, Kunz RK, Human J, Chen N, Bürli R, Hungate R, Novak P, Itano A, Zhang X, Yu V, Nguyen Y, Tudor Y, Plant M, Flynn S, Xu Y, Meagher KL, Whittington DA, Ng GY. Hu E, et al. J Med Chem. 2008 Jun 12;51(11):3065-8. doi: 10.1021/jm800188g. Epub 2008 May 1. J Med Chem. 2008. PMID: 18447379

5

Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity.

Martin MW, Newcomb J, Nunes JJ, McGowan DC, Armistead DM, Boucher C, Buchanan JL, Buckner W, Chai L, Elbaum D, Epstein LF, Faust T, Flynn S, Gallant P, Gore A, Gu Y, Hsieh F, Huang X, Lee JH, Metz D, Middleton S, Mohn D, Morgenstern K, Morrison MJ, Novak PM, Oliveira-dos-Santos A, Powers D, Rose P, Schneider S, Sell S, Tudor Y, Turci SM, Welcher AA, White RD, Zack D, Zhao H, Zhu L, Zhu X, Ghiron C, Amouzegh P, Ermann M, Jenkins J, Johnston D, Napier S, Power E. Martin MW, et al. Among authors: novak pm. J Med Chem. 2006 Aug 10;49(16):4981-91. doi: 10.1021/jm060435i. J Med Chem. 2006. PMID: 16884310

6

Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors.

Buchanan JL, Newcomb JR, Carney DP, Chaffee SC, Chai L, Cupples R, Epstein LF, Gallant P, Gu Y, Harmange JC, Hodge K, Houk BE, Huang X, Jona J, Joseph S, Jun HT, Kumar R, Li C, Lu J, Menges T, Morrison MJ, Novak PM, van der Plas S, Radinsky R, Rose PE, Sawant S, Sun JR, Surapaneni S, Turci SM, Xu K, Yanez E, Zhao H, Zhu X. Buchanan JL, et al. Among authors: novak pm. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2394-9. doi: 10.1016/j.bmcl.2011.02.075. Epub 2011 Feb 23. Bioorg Med Chem Lett. 2011. PMID: 21414779

7

Design, synthesis, and conformational analysis of a novel series of HIV protease inhibitors.

Baker CT, Salituro FG, Court JJ, Deininger DD, Kim EE, Li B, Novak PM, Rao BG, Pazhanisamy S, Schairer WC, Tung RD. Baker CT, et al. Among authors: novak pm. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3631-6. doi: 10.1016/s0960-894x(98)00669-6. Bioorg Med Chem Lett. 1998. PMID: 9934484

8

Design and synthesis of novel conformationally restricted HIV protease inhibitors.

Salituro FG, Baker CT, Court JJ, Deininger DD, Kim EE, Li B, Novak PM, Rao BG, Pazhanisamy S, Porter MD, Schairer WC, Tung RD. Salituro FG, et al. Among authors: novak pm. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3637-42. doi: 10.1016/s0960-894x(98)00670-2. Bioorg Med Chem Lett. 1998. PMID: 9934485

9

Optimization of novel di-substituted cyclohexylbenzamide derivatives as potent 11 beta-HSD1 inhibitors.

McMinn DL, Rew Y, Sudom A, Caille S, Degraffenreid M, He X, Hungate R, Jiang B, Jaen J, Julian LD, Kaizerman J, Novak P, Sun D, Tu H, Ursu S, Walker NP, Yan X, Ye Q, Wang Z, Powers JP. McMinn DL, et al. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1446-50. doi: 10.1016/j.bmcl.2009.01.026. Epub 2009 Jan 15. Bioorg Med Chem Lett. 2009. PMID: 19185488

10

Ecological half-life of radiocesium in white-tailed deer on the Department of Energy's Savannah River Site: What can a half century of field monitoring tell us?

Gaines KF, Novak PM, Novak JM. Gaines KF, et al. Among authors: novak pm. J Environ Radioact. 2021 Sep;235-236:106654. doi: 10.1016/j.jenvrad.2021.106654. Epub 2021 May 24. J Environ Radioact. 2021. PMID: 34044289

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