Ghai RD - Search Results

1

Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor.

MacPherson LJ, Bayburt EK, Capparelli MP, Bohacek RS, Clarke FH, Ghai RD, Sakane Y, Berry CJ, Peppard JV, Trapani AJ. MacPherson LJ, et al. Among authors: ghai rd. J Med Chem. 1993 Nov 26;36(24):3821-8. doi: 10.1021/jm00076a009. J Med Chem. 1993. PMID: 8254611

2

Characterisation of neutral endopeptidase 3.4.24.11 (NEP) in the kidney: comparison between normotensive, genetically hypertensive and experimentally hypertensive rats.

Schulz R, Sakane Y, Berry C, Ghai R. Schulz R, et al. J Enzyme Inhib. 1991;4(4):347-58. doi: 10.3109/14756369109030399. J Enzyme Inhib. 1991. PMID: 1669834

3

Enkephalinase inhibitors. 1. 2,4-Dibenzylglutaric acid derivatives.

Ksander GM, Diefenbacher CG, Yuan AM, Clark F, Sakane Y, Ghai RD. Ksander GM, et al. Among authors: ghai rd. J Med Chem. 1989 Dec;32(12):2519-26. doi: 10.1021/jm00132a005. J Med Chem. 1989. PMID: 2585440

4

Pharmacologic profile of CGS 24128, a potent, long-acting inhibitor of neutral endopeptidase 24.11.

Trapani AJ, Beil ME, Coté DT, de Lombaert S, Erion MD, Gerlock TE, Ghai RD, Hopkins MF, Peppard JV, Webb RL, et al. Trapani AJ, et al. Among authors: ghai rd. J Cardiovasc Pharmacol. 1994 Mar;23(3):358-64. J Cardiovasc Pharmacol. 1994. PMID: 7515977

5

A rapid indirect method to determine the plasma concentrations of neutral endopeptidase inhibitors.

Ghai RD, De Lombaert S, Ksander GM, Berry C, Sakane Y, Trapani AJ. Ghai RD, et al. Res Commun Mol Pathol Pharmacol. 1995 Feb;87(2):211-20. Res Commun Mol Pathol Pharmacol. 1995. PMID: 7749658

6

Dicarboxylic acid dipeptide neutral endopeptidase inhibitors.

Ksander GM, Ghai RD, deJesus R, Diefenbacher CG, Yuan A, Berry C, Sakane Y, Trapani A. Ksander GM, et al. Among authors: ghai rd. J Med Chem. 1995 May 12;38(10):1689-700. doi: 10.1021/jm00010a014. J Med Chem. 1995. PMID: 7752193

7

Pharmacological profile of a non-peptidic dual inhibitor of neutral endopeptidase 24.11 and endothelin-converting enzyme.

De Lombaert S, Ghai RD, Jeng AY, Trapani AJ, Webb RL. De Lombaert S, et al. Among authors: ghai rd. Biochem Biophys Res Commun. 1994 Oct 14;204(1):407-12. doi: 10.1006/bbrc.1994.2473. Biochem Biophys Res Commun. 1994. PMID: 7945387

8

N-Phosphonomethyl dipeptides and their phosphonate prodrugs, a new generation of neutral endopeptidase (NEP, EC 3.4.24.11) inhibitors.

De Lombaert S, Erion MD, Tan J, Blanchard L, el-Chehabi L, Ghai RD, Sakane Y, Berry C, Trapani AJ. De Lombaert S, et al. Among authors: ghai rd. J Med Chem. 1994 Feb 18;37(4):498-511. doi: 10.1021/jm00030a009. J Med Chem. 1994. PMID: 8120868

9

The pharmacology of CGS 25462: a potent, orally bioavailable, long-acting inhibitor of neutral endopeptidase 24.11.

Trapani AJ, De Lombaert S, Erion MD, Ghai RD, Peppard JV, Lappe RW, Worcel M. Trapani AJ, et al. Among authors: ghai rd. J Hypertens Suppl. 1993 Dec;11(5):S220-1. J Hypertens Suppl. 1993. PMID: 8158354 No abstract available.

10

Heterocyclic lactam derivatives as dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibitors.

Stanton JL, Sperbeck DM, Trapani AJ, Cote D, Sakane Y, Berry CJ, Ghai RD. Stanton JL, et al. Among authors: ghai rd. J Med Chem. 1993 Nov 26;36(24):3829-33. doi: 10.1021/jm00076a010. J Med Chem. 1993. PMID: 8254612

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