Wilks A - Search Results

1

Proton NMR investigation of substrate-bound heme oxygenase: evidence for electronic and steric contributions to stereoselective heme cleavage.

Hernández G, Wilks A, Paolesse R, Smith KM, Ortiz de Montellano PR, La Mar GN. Hernández G, et al. Among authors: wilks a. Biochemistry. 1994 May 31;33(21):6631-41. doi: 10.1021/bi00187a033. Biochemistry. 1994. PMID: 8204600

2

Solution NMR characterization of an unusual distal H-bond network in the active site of the cyanide-inhibited, human heme oxygenase complex of the symmetric substrate, 2,4-dimethyldeuterohemin.

Li Y, Syvitski RT, Auclair K, Wilks A, Ortiz De Montellano PR, La Mar GN. Li Y, et al. Among authors: wilks a. J Biol Chem. 2002 Sep 6;277(36):33018-31. doi: 10.1074/jbc.M204216200. Epub 2002 Jun 17. J Biol Chem. 2002. PMID: 12070167 Free article.

3

Expression and characterization of truncated human heme oxygenase (hHO-1) and a fusion protein of hHO-1 with human cytochrome P450 reductase.

Wilks A, Black SM, Miller WL, Ortiz de Montellano PR. Wilks A, et al. Biochemistry. 1995 Apr 4;34(13):4421-7. doi: 10.1021/bi00013a034. Biochemistry. 1995. PMID: 7703255

4

Identification of histidine 25 as the heme ligand in human liver heme oxygenase.

Sun J, Loehr TM, Wilks A, Ortiz de Montellano PR. Sun J, et al. Among authors: wilks a. Biochemistry. 1994 Nov 22;33(46):13734-40. doi: 10.1021/bi00250a026. Biochemistry. 1994. PMID: 7947784

5

Heme oxygenase (HO-1). Evidence for electrophilic oxygen addition to the porphyrin ring in the formation of alpha-meso-hydroxyheme.

Wilks A, Torpey J, Ortiz de Montellano PR. Wilks A, et al. J Biol Chem. 1994 Nov 25;269(47):29553-6. J Biol Chem. 1994. PMID: 7961940 Free article.

6

Rat liver heme oxygenase. High level expression of a truncated soluble form and nature of the meso-hydroxylating species.

Wilks A, Ortiz de Montellano PR. Wilks A, et al. J Biol Chem. 1993 Oct 25;268(30):22357-62. J Biol Chem. 1993. PMID: 8226746 Free article.

7

Resonance Raman and EPR spectroscopic studies on heme-heme oxygenase complexes.

Sun J, Wilks A, Ortiz de Montellano PR, Loehr TM. Sun J, et al. Among authors: wilks a. Biochemistry. 1993 Dec 28;32(51):14151-7. doi: 10.1021/bi00214a012. Biochemistry. 1993. PMID: 8260499

8

Heme oxygenase (HO-1): His-132 stabilizes a distal water ligand and assists catalysis.

Wilks A, Ortiz de Montellano PR, Sun J, Loehr TM. Wilks A, et al. Biochemistry. 1996 Jan 23;35(3):930-6. doi: 10.1021/bi952405f. Biochemistry. 1996. PMID: 8547275

9

Heme oxygenase active-site residues identified by heme-protein cross-linking during reduction of CBrCl3.

Wilks A, Medzihradszky KF, Ortiz de Montellano PR. Wilks A, et al. Biochemistry. 1998 Mar 3;37(9):2889-96. doi: 10.1021/bi972720x. Biochemistry. 1998. PMID: 9485440

10

Replacement of the proximal histidine iron ligand by a cysteine or tyrosine converts heme oxygenase to an oxidase.

Liu Y, Moënne-Loccoz P, Hildebrand DP, Wilks A, Loehr TM, Mauk AG, Ortiz de Montellano PR. Liu Y, et al. Among authors: wilks a. Biochemistry. 1999 Mar 23;38(12):3733-43. doi: 10.1021/bi982707s. Biochemistry. 1999. PMID: 10090762

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