Kosugi S - Search Results

1

Possible difference in glycosylation of the thyrotropin receptor among species.

Kosugi S, Akamizu T, Mori T. Kosugi S, et al. Biochem Biophys Res Commun. 1994 May 16;200(3):1207-13. doi: 10.1006/bbrc.1994.1579. Biochem Biophys Res Commun. 1994. PMID: 8185569

2

Molecular basis for the autoreactivity against thyroid stimulating hormone receptor.

Kohn LD, Kosugi S, Ban T, Saji M, Ikuyama S, Giuliani C, Hidaka A, Shimura H, Akamizu T, Tahara K, et al. Kohn LD, et al. Among authors: kosugi s. Int Rev Immunol. 1992;9(2):135-65. doi: 10.3109/08830189209061788. Int Rev Immunol. 1992. PMID: 1283175 Review.

3

Role of cysteine residues in the extracellular domain and exoplasmic loops of the transmembrane domain of the TSH receptor: effect of mutation to serine on TSH receptor activity and response to thyroid stimulating autoantibodies.

Kosugi S, Ban T, Akamizu T, Kohn LD. Kosugi S, et al. Biochem Biophys Res Commun. 1992 Dec 30;189(3):1754-62. doi: 10.1016/0006-291x(92)90281-o. Biochem Biophys Res Commun. 1992. PMID: 1336379

4

Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid-stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxedema: these determinants have no homologous sequence on gonadotropin receptors.

Kosugi S, Ban T, Akamizu T, Kohn LD. Kosugi S, et al. Mol Endocrinol. 1992 Feb;6(2):168-80. doi: 10.1210/mend.6.2.1349156. Mol Endocrinol. 1992. PMID: 1349156

5

Site-directed mutagenesis of a portion of the extracellular domain of the rat thyrotropin receptor important in autoimmune thyroid disease and nonhomologous with gonadotropin receptors. Relationship of functional and immunogenic domains.

Kosugi S, Ban T, Akamizu T, Kohn LD. Kosugi S, et al. J Biol Chem. 1991 Oct 15;266(29):19413-8. J Biol Chem. 1991. PMID: 1655787 Free article.

6

Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies.

Akamizu T, Ikuyama S, Saji M, Kosugi S, Kozak C, McBride OW, Kohn LD. Akamizu T, et al. Among authors: kosugi s. Proc Natl Acad Sci U S A. 1990 Aug;87(15):5677-81. doi: 10.1073/pnas.87.15.5677. Proc Natl Acad Sci U S A. 1990. PMID: 1696008 Free PMC article.

7

Further characterization of a high affinity thyrotropin binding site on the rat thyrotropin receptor which is an epitope for blocking antibodies from idiopathic myxedema patients but not thyroid stimulating antibodies from Graves' patients.

Kosugi S, Ban T, Akamizu T, Kohn LD. Kosugi S, et al. Biochem Biophys Res Commun. 1991 Oct 31;180(2):1118-24. doi: 10.1016/s0006-291x(05)81182-9. Biochem Biophys Res Commun. 1991. PMID: 1719963

8

The extracellular domain of the TSH receptor has an immunogenic epitope reactive with Graves' IgG but unrelated to receptor function as well as determinants having different roles for high affinity TSH binding and the activity of thyroid-stimulating autoantibodies.

Kosugi S, Akamizu T, Takai O, Prabhakar BS, Kohn LD. Kosugi S, et al. Thyroid. 1991 Winter;1(4):321-30. doi: 10.1089/thy.1991.1.321. Thyroid. 1991. PMID: 1726785

9

The TSH receptor in autoimmune Basedow's disease.

Akamizu T, Saji M, Ikuyama S, Kosugi S, Tahara K, Kohn LD. Akamizu T, et al. Among authors: kosugi s. Exp Clin Endocrinol. 1991 May;97(2-3):153-9. doi: 10.1055/s-0029-1211055. Exp Clin Endocrinol. 1991. PMID: 1915626 Review.

10

Thyrotropin receptor processing and interaction with thyrotropin.

Akamizu T, Kosugi S, Kohn LD. Akamizu T, et al. Among authors: kosugi s. Biochem Biophys Res Commun. 1990 Jun 29;169(3):947-52. doi: 10.1016/0006-291x(90)91985-2. Biochem Biophys Res Commun. 1990. PMID: 2114112

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