Hoyer D - Search Results

1

P1 aspartate-based peptide alpha-((2,6-dichlorobenzoyl)oxy)methyl ketones as potent time-dependent inhibitors of interleukin-1 beta-converting enzyme.

Dolle RE, Hoyer D, Prasad CV, Schmidt SJ, Helaszek CT, Miller RE, Ator MA. Dolle RE, et al. Among authors: hoyer d. J Med Chem. 1994 Mar 4;37(5):563-4. doi: 10.1021/jm00031a003. J Med Chem. 1994. PMID: 8126694 No abstract available.

2

Aspartyl alpha-((1-phenyl-3-(trifluoromethyl)-pyrazol-5-yl)oxy)methyl ketones as interleukin-1 beta converting enzyme inhibitors. Significance of the P1 and P3 amido nitrogens for enzyme-peptide inhibitor binding.

Dolle RE, Singh J, Rinker J, Hoyer D, Prasad CV, Graybill TL, Salvino JM, Helaszek CT, Miller RE, Ator MA. Dolle RE, et al. Among authors: hoyer d. J Med Chem. 1994 Nov 11;37(23):3863-6. doi: 10.1021/jm00049a001. J Med Chem. 1994. PMID: 7966144 No abstract available.

3

Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1 beta-converting enzyme inhibitor.

Dolle RE, Prasad CV, Prouty CP, Salvino JM, Awad MM, Schmidt SJ, Hoyer D, Ross TM, Graybill TL, Speier GJ, Uhl J, Miller BE, Helaszek CT, Ator MA. Dolle RE, et al. Among authors: hoyer d. J Med Chem. 1997 Jun 20;40(13):1941-6. doi: 10.1021/jm9701637. J Med Chem. 1997. PMID: 9207934 No abstract available.

4

Potent and selective non-peptidic inhibitors of endothelin-converting enzyme-1 with sustained duration of action.

De Lombaert S, Blanchard L, Stamford LB, Tan J, Wallace EM, Satoh Y, Fitt J, Hoyer D, Simonsbergen D, Moliterni J, Marcopoulos N, Savage P, Chou M, Trapani AJ, Jeng AY. De Lombaert S, et al. Among authors: hoyer d. J Med Chem. 2000 Feb 10;43(3):488-504. doi: 10.1021/jm990507o. J Med Chem. 2000. PMID: 10669576

5

Design and synthesis of potent thiol-based inhibitors of endothelin converting enzyme-1.

Fink CA, Moskal M, Firooznia F, Hoyer D, Symonsbergen D, Wei D, Qiao Y, Savage P, Beil ME, Trapani AJ, Jeng AY. Fink CA, et al. Among authors: hoyer d. Bioorg Med Chem Lett. 2000 Sep 4;10(17):2037-9. doi: 10.1016/s0960-894x(00)00403-0. Bioorg Med Chem Lett. 2000. PMID: 10987444

6

Peptide folding induces high and selective affinity of a linear and small beta-peptide to the human somatostatin receptor 4.

Gademann K, Kimmerlin T, Hoyer D, Seebach D. Gademann K, et al. Among authors: hoyer d. J Med Chem. 2001 Jul 19;44(15):2460-8. doi: 10.1021/jm010816q. J Med Chem. 2001. PMID: 11448228

7

CGS 34226, a thiol-based dual inhibitor of endothelin converting enzyme-1 and neutral endopeptidase 24.11.

Jeng AY, Savage P, Beil ME, Bruseo CW, Hoyer D, Fink CA, Trapani AJ. Jeng AY, et al. Among authors: hoyer d. Clin Sci (Lond). 2002 Aug;103 Suppl 48:98S-101S. doi: 10.1042/CS103S098S. Clin Sci (Lond). 2002. PMID: 12193064

8

Effects of the ECE/NEP inhibitor CGS 34225 on the big ET-1-induced pressor response and plasma atrial natriuretic peptide concentration in conscious rats.

Trapani AJ, Beil ME, Bruseo CW, Fink CA, Hoyer D, Savage P, Jeng AY. Trapani AJ, et al. Among authors: hoyer d. Clin Sci (Lond). 2002 Aug;103 Suppl 48:102S-106S. doi: 10.1042/CS103S102S. Clin Sci (Lond). 2002. PMID: 12193065

9

A γ-Lactam Siderophore Antibiotic Effective against Multidrug-Resistant Gram-Negative Bacilli.

Goldberg JA, Nguyen H, Kumar V, Spencer EJ, Hoyer D, Marshall EK, Cmolik A, O'Shea M, Marshall SH, Hujer AM, Hujer KM, Rudin SD, Domitrovic TN, Bethel CR, Papp-Wallace KM, Logan LK, Perez F, Jacobs MR, van Duin D, Kreiswirth BM, Bonomo RA, Plummer MS, van den Akker F. Goldberg JA, et al. Among authors: hoyer d. J Med Chem. 2020 Jun 11;63(11):5990-6002. doi: 10.1021/acs.jmedchem.0c00255. Epub 2020 Jun 2. J Med Chem. 2020. PMID: 32420736 Free PMC article.

10

A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp.

Goldberg JA, Kumar V, Spencer EJ, Hoyer D, Marshall SH, Hujer AM, Hujer KM, Bethel CR, Papp-Wallace KM, Perez F, Jacobs MR, van Duin D, Kreiswirth BN, van den Akker F, Plummer MS, Bonomo RA. Goldberg JA, et al. Among authors: hoyer d. Eur J Med Chem. 2021 Aug 5;220:113436. doi: 10.1016/j.ejmech.2021.113436. Epub 2021 Apr 8. Eur J Med Chem. 2021. PMID: 33933754 Free PMC article.

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