Wedley S - Search Results

1

Synthesis and dopamine antagonist activity of 2-thioether derivatives of the ergoline ring system.

Tupper DE, Pullar IA, Clemens JA, Fairhurst J, Risius FC, Timms GH, Wedley S. Tupper DE, et al. Among authors: wedley s. J Med Chem. 1993 Apr 2;36(7):912-8. doi: 10.1021/jm00059a017. J Med Chem. 1993. PMID: 8096548

2

SAR development of a selective 5-HT1D antagonist/serotonin reuptake inhibitor lead using rapid parallel synthesis.

Timms GH, Boot JR, Broadmore RJ, Carney SL, Cooper J, Findlay JD, Gilmore J, Mitchell S, Moore NA, Pullar I, Sanger GJ, Tomlinson R, Tree BB, Wedley S. Timms GH, et al. Among authors: wedley s. Bioorg Med Chem Lett. 2004 May 17;14(10):2469-72. doi: 10.1016/j.bmcl.2004.03.003. Bioorg Med Chem Lett. 2004. PMID: 15109634

3

Effects of conformationally restricted 4-piperazinyl-10H-thienobenzodiazepine neuroleptics on central dopaminergic and cholinergic systems.

Chakrabarti JK, Hotten TM, Morgan SE, Pullar IA, Rackham DM, Risius FC, Wedley S, Chaney MO, Jones ND. Chakrabarti JK, et al. Among authors: wedley s. J Med Chem. 1982 Oct;25(10):1133-40. doi: 10.1021/jm00352a007. J Med Chem. 1982. PMID: 6128416

4

omega-Agatoxin IVA identifies a single calcium channel subtype which contributes to the potassium-induced release of acetylcholine, 5-hydroxytryptamine, dopamine, gamma-aminobutyric acid and glutamate from rat brain slices.

Harvey J, Wedley S, Findlay JD, Sidell MR, Pullar IA. Harvey J, et al. Among authors: wedley s. Neuropharmacology. 1996 Apr;35(4):385-92. doi: 10.1016/0028-3908(96)00010-x. Neuropharmacology. 1996. PMID: 8793900

5

LY367265, an inhibitor of the 5-hydroxytryptamine transporter and 5-hydroxytryptamine(2A) receptor antagonist: a comparison with the antidepressant, nefazodone.

Pullar IA, Carney SL, Colvin EM, Lucaites VL, Nelson DL, Wedley S. Pullar IA, et al. Among authors: wedley s. Eur J Pharmacol. 2000 Oct 27;407(1-2):39-46. doi: 10.1016/s0014-2999(00)00728-7. Eur J Pharmacol. 2000. PMID: 11050288

6

In vitro activity of LY393558, an inhibitor of the 5-hydroxytryptamine transporter with 5-HT(1B/1D/2) receptor antagonist properties.

Pullar IA, Boot JR, Carney SL, Cohen ML, Colvin EM, Conway RG, Hardy CH, Lucaites VL, Nelson DL, Schenck KW, Tomlinson R, Wedley S. Pullar IA, et al. Among authors: wedley s. Eur J Pharmacol. 2001 Nov 30;432(1):9-17. doi: 10.1016/s0014-2999(01)01468-6. Eur J Pharmacol. 2001. PMID: 11734182

7

The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig.

Pullar IA, Boot JR, Broadmore RJ, Eyre TA, Cooper J, Sanger GJ, Wedley S, Mitchell SN. Pullar IA, et al. Among authors: wedley s. Eur J Pharmacol. 2004 Jun 16;493(1-3):85-93. doi: 10.1016/j.ejphar.2004.04.029. Eur J Pharmacol. 2004. PMID: 15189767

8

The effects of standard neuroleptic compounds on the binding of 3H-spiroperidol in the striatum and mesolimbic system of the rat in vitro.

Howard JL, Large BT, Wedley S, Pullar IA. Howard JL, et al. Among authors: wedley s. Life Sci. 1978 Aug 14;23(6):599-603. doi: 10.1016/0024-3205(78)90039-5. Life Sci. 1978. PMID: 29198 No abstract available.

9

Actions of arginine polyamine on voltage and ligand-activated whole cell currents recorded from cultured neurones.

Scott RH, Sweeney MI, Kobrinsky EM, Pearson HA, Timms GH, Pullar IA, Wedley S, Dolphin AC. Scott RH, et al. Among authors: wedley s. Br J Pharmacol. 1992 May;106(1):199-207. doi: 10.1111/j.1476-5381.1992.tb14315.x. Br J Pharmacol. 1992. PMID: 1380382 Free PMC article.

10

The inhibition of monoamine uptake into rat brain synaptosomess by selected bicyclo-octanes and an analogous bicyclo-octene.

Wedley S, Howard JL, Large BT, Pullar IA. Wedley S, et al. Biochem Pharmacol. 1978;27(24):2907-9. doi: 10.1016/0006-2952(78)90207-1. Biochem Pharmacol. 1978. PMID: 736983 No abstract available.

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