Francklyn C - Search Results

1

Crystallization of histidyl-tRNA synthetase from Escherichia coli.

Francklyn C, Harris D, Moras D. Francklyn C, et al. J Mol Biol. 1994 Aug 12;241(2):275-7. doi: 10.1006/jmbi.1994.1498. J Mol Biol. 1994. PMID: 8057367

2

Crystal structure of histidyl-tRNA synthetase from Escherichia coli complexed with histidyl-adenylate.

Arnez JG, Harris DC, Mitschler A, Rees B, Francklyn CS, Moras D. Arnez JG, et al. Among authors: francklyn cs. EMBO J. 1995 Sep 1;14(17):4143-55. doi: 10.1002/j.1460-2075.1995.tb00088.x. EMBO J. 1995. PMID: 7556055 Free PMC article.

3

Cytosine 73 is a discriminator nucleotide in vivo for histidyl-tRNA in Escherichia coli.

Yan W, Francklyn C. Yan W, et al. Among authors: francklyn c. J Biol Chem. 1994 Apr 1;269(13):10022-7. J Biol Chem. 1994. PMID: 8144499 Free article.

4

A tRNA identity switch mediated by the binding interaction between a tRNA anticodon and the accessory domain of a class II aminoacyl-tRNA synthetase.

Yan W, Augustine J, Francklyn C. Yan W, et al. Among authors: francklyn c. Biochemistry. 1996 May 28;35(21):6559-68. doi: 10.1021/bi952889f. Biochemistry. 1996. PMID: 8639604

5

tRNA selection by a class II aminoacyl-tRNA synthetase: the role of accessory domains and inter-domain communication in RNA recognition.

Yan W, Francklyn C. Yan W, et al. Among authors: francklyn c. Nucleic Acids Symp Ser. 1995;(33):167-9. Nucleic Acids Symp Ser. 1995. PMID: 8643360

6

Design of an active fragment of a class II aminoacyl-tRNA synthetase and its significance for synthetase evolution.

Augustine J, Francklyn C. Augustine J, et al. Among authors: francklyn c. Biochemistry. 1997 Mar 25;36(12):3473-82. doi: 10.1021/bi962395y. Biochemistry. 1997. PMID: 9131996

7

The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase.

Arnez JG, Augustine JG, Moras D, Francklyn CS. Arnez JG, et al. Among authors: francklyn cs. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7144-9. doi: 10.1073/pnas.94.14.7144. Proc Natl Acad Sci U S A. 1997. PMID: 9207058 Free PMC article.

8

Catalytic defects in mutants of class II histidyl-tRNA synthetase from Salmonella typhimurium previously linked to decreased control of histidine biosynthesis regulation.

Francklyn C, Adams J, Augustine J. Francklyn C, et al. J Mol Biol. 1998 Jul 31;280(5):847-58. doi: 10.1006/jmbi.1998.1902. J Mol Biol. 1998. PMID: 9671554

9

An aminoacyl-tRNA synthetase paralog with a catalytic role in histidine biosynthesis.

Sissler M, Delorme C, Bond J, Ehrlich SD, Renault P, Francklyn C. Sissler M, et al. Among authors: francklyn c. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8985-90. doi: 10.1073/pnas.96.16.8985. Proc Natl Acad Sci U S A. 1999. PMID: 10430882 Free PMC article.

10

tRNA discrimination at the binding step by a class II aminoacyl-tRNA synthetase.

Bovee ML, Yan W, Sproat BS, Francklyn CS. Bovee ML, et al. Among authors: francklyn cs. Biochemistry. 1999 Oct 12;38(41):13725-35. doi: 10.1021/bi991182g. Biochemistry. 1999. PMID: 10521280

Additional filter binding studies showed tighter binding of both cognate and noncognate tRNAs by G405D mutant HisRS [Yan, W., Augustine, J., and Francklyn, C. (1996) Biochemistry 35, 6559], which possesses a single amino acid change in the C-terminal anticodo …

Additional filter binding studies showed tighter binding of both cognate and noncognate tRNAs by G405D mutant HisRS [Yan, W., Augustine, J., …

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