Jhoti H - Search Results

1

X-ray crystallographic studies of a series of penicillin-derived asymmetric inhibitors of HIV-1 protease.

Jhoti H, Singh OM, Weir MP, Cooke R, Murray-Rust P, Wonacott A. Jhoti H, et al. Biochemistry. 1994 Jul 19;33(28):8417-27. doi: 10.1021/bi00194a005. Biochemistry. 1994. PMID: 8031777

2

A series of penicillin-derived C2-symmetric inhibitors of HIV-1 proteinase: structural and modeling studies.

Wonacott A, Cooke R, Hayes FR, Hann MM, Jhoti H, McMeekin P, Mistry A, Murray-Rust P, Singh OM, Weir MP. Wonacott A, et al. Among authors: jhoti h. J Med Chem. 1993 Oct 15;36(21):3113-9. doi: 10.1021/jm00073a010. J Med Chem. 1993. PMID: 8230097

3

Novel natural product 5,5-trans-lactone inhibitors of human alpha-thrombin: mechanism of action and structural studies.

Weir MP, Bethell SS, Cleasby A, Campbell CJ, Dennis RJ, Dix CJ, Finch H, Jhoti H, Mooney CJ, Patel S, Tang CM, Ward M, Wonacott AJ, Wharton CW. Weir MP, et al. Among authors: jhoti h. Biochemistry. 1998 May 12;37(19):6645-57. doi: 10.1021/bi972499o. Biochemistry. 1998. PMID: 9578548

4

Crystal structures of thrombin complexed to a novel series of synthetic inhibitors containing a 5,5-trans-lactone template.

Jhoti H, Cleasby A, Reid S, Thomas PJ, Weir M, Wonacott A. Jhoti H, et al. Biochemistry. 1999 Jun 22;38(25):7969-77. doi: 10.1021/bi9830359. Biochemistry. 1999. PMID: 10387040

5

X-ray crystal structure of human dopamine sulfotransferase, SULT1A3. Molecular modeling and quantitative structure-activity relationship analysis demonstrate a molecular basis for sulfotransferase substrate specificity.

Dajani R, Cleasby A, Neu M, Wonacott AJ, Jhoti H, Hood AM, Modi S, Hersey A, Taskinen J, Cooke RM, Manchee GR, Coughtrie MW. Dajani R, et al. Among authors: jhoti h. J Biol Chem. 1999 Dec 31;274(53):37862-8. doi: 10.1074/jbc.274.53.37862. J Biol Chem. 1999. PMID: 10608851 Free article.

6

Crystallization and preliminary X-ray diffraction studies on ADP-ribosylation factor 1.

Greasley S, Jhoti H, Fensome AC, Cockcroft S, Thomas GM, Bax B. Greasley S, et al. Among authors: jhoti h. J Mol Biol. 1994 Dec 16;244(5):651-3. doi: 10.1006/jmbi.1994.1759. J Mol Biol. 1994. PMID: 7990146

7

The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms.

Greasley SE, Jhoti H, Teahan C, Solari R, Fensome A, Thomas GM, Cockcroft S, Bax B. Greasley SE, et al. Among authors: jhoti h. Nat Struct Biol. 1995 Sep;2(9):797-806. doi: 10.1038/nsb0995-797. Nat Struct Biol. 1995. PMID: 7552752

8

Molecular structure of serum transferrin at 3.3-A resolution.

Bailey S, Evans RW, Garratt RC, Gorinsky B, Hasnain S, Horsburgh C, Jhoti H, Lindley PF, Mydin A, Sarra R, et al. Bailey S, et al. Among authors: jhoti h. Biochemistry. 1988 Jul 26;27(15):5804-12. doi: 10.1021/bi00415a061. Biochemistry. 1988. PMID: 3179277

9

The discovery of novel protein kinase inhibitors by using fragment-based high-throughput x-ray crystallography.

Gill A, Cleasby A, Jhoti H. Gill A, et al. Among authors: jhoti h. Chembiochem. 2005 Mar;6(3):506-12. doi: 10.1002/cbic.200400188. Chembiochem. 2005. PMID: 15696598 Review.

10

Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors.

Howard N, Abell C, Blakemore W, Chessari G, Congreve M, Howard S, Jhoti H, Murray CW, Seavers LC, van Montfort RL. Howard N, et al. Among authors: jhoti h. J Med Chem. 2006 Feb 23;49(4):1346-55. doi: 10.1021/jm050850v. J Med Chem. 2006. PMID: 16480269

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