Christians U - Search Results

1

Use of organotypical cultures of primary hepatocytes to analyse drug biotransformation in man and animals.

Bader A, Zech K, Crome O, Christians U, Ringe B, Pichlmayr R, Sewing KF. Bader A, et al. Among authors: christians u. Xenobiotica. 1994 Jul;24(7):623-33. doi: 10.3109/00498259409043265. Xenobiotica. 1994. PMID: 7975727

2

Tacrolimus (FK 506) biotransformation in primary rat hepatocytes depends on extracellular matrix geometry.

Bader A, Knop E, Böker KH, Crome O, Frühauf N, Gonschior AK, Christians U, Esselmann H, Pichlmayr R, Sewing KF. Bader A, et al. Among authors: christians u. Naunyn Schmiedebergs Arch Pharmacol. 1996 Mar;353(4):461-73. doi: 10.1007/BF00261444. Naunyn Schmiedebergs Arch Pharmacol. 1996. PMID: 8935714

3

Biotransformation of cyclosporin in primary rat, porcine and human liver cell co-cultures.

Schmelzer E, Acikgoez A, Frühauf NR, Crome O, Klempnauer J, Christians U, Bader A. Schmelzer E, et al. Among authors: christians u. Xenobiotica. 2006 Aug;36(8):693-708. doi: 10.1080/00498250600674410. Xenobiotica. 2006. PMID: 16891250

4

Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat.

Sattler M, Guengerich FP, Yun CH, Christians U, Sewing KF. Sattler M, et al. Among authors: christians u. Drug Metab Dispos. 1992 Sep-Oct;20(5):753-61. Drug Metab Dispos. 1992. PMID: 1385058

5

Investigations on the metabolic pathways of cyclosporine: I. Excretion of cyclosporine and its metabolites in human bile--isolation of 12 new cyclosporine metabolites.

Christians U, Strohmeyer S, Kownatzki R, Schiebel HM, Bleck J, Greipel J, Kohlhaw K, Schottmann R, Sewing KF. Christians U, et al. Xenobiotica. 1991 Sep;21(9):1185-98. doi: 10.3109/00498259109039559. Xenobiotica. 1991. PMID: 1788987

6

Investigations on the metabolic pathways of cyclosporine: II. Elucidation of the metabolic pathways in vitro by human liver microsomes.

Christians U, Strohmeyer S, Kownatzki R, Schiebel HM, Bleck J, Kohlhaw K, Schottmann R, Sewing KF. Christians U, et al. Xenobiotica. 1991 Sep;21(9):1199-210. doi: 10.3109/00498259109039560. Xenobiotica. 1991. PMID: 1788988

7

Cyclosporin metabolism in transplant patients.

Christians U, Sewing KF. Christians U, et al. Pharmacol Ther. 1993 Feb-Mar;57(2-3):291-345. doi: 10.1016/0163-7258(93)90059-m. Pharmacol Ther. 1993. PMID: 8361996 Review.

8

An organotypical in vitro model of the liver parenchyma for uptake studies of diagnostic MR receptor agents.

Bader A, Reimer P, Knop E, Böker K, Christians U, Weissleder R, Sewing KF. Bader A, et al. Among authors: christians u. Magn Reson Imaging. 1995;13(7):991-1002. doi: 10.1016/0730-725x(95)00053-j. Magn Reson Imaging. 1995. PMID: 8583878

9

Alternative cyclosporine metabolic pathways and toxicity.

Christians U, Sewing KF. Christians U, et al. Clin Biochem. 1995 Dec;28(6):547-59. doi: 10.1016/0009-9120(95)00037-3. Clin Biochem. 1995. PMID: 8595701 Review.

10

Reconstruction of liver tissue in vitro: geometry of characteristic flat bed, hollow fiber, and spouted bed bioreactors with reference to the in vivo liver.

Bader A, Knop E, Frühauf N, Crome O, Böker K, Christians U, Oldhafer K, Ringe B, Pichlmayr R, Sewing KF. Bader A, et al. Among authors: christians u. Artif Organs. 1995 Sep;19(9):941-50. doi: 10.1111/j.1525-1594.1995.tb02456.x. Artif Organs. 1995. PMID: 8687303

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