Tachibana K - Search Results

1

A highly enhanced thrombopoietic activity by monomethoxy polyethylene glycol-modified recombinant human interleukin-6.

Inoue H, Kadoya T, Kabaya K, Tachibana K, Nishi N, Sato M, Ohsawa M, Mikayama T, Mori KJ. Inoue H, et al. Among authors: tachibana k. J Lab Clin Med. 1994 Oct;124(4):529-36. J Lab Clin Med. 1994. PMID: 7930877

2

Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity.

Sudo T, Tachibana K, Toga K, Tochizawa S, Inoue Y, Kimura Y, Hidaka H. Sudo T, et al. Among authors: tachibana k. Biochem Pharmacol. 2000 Feb 15;59(4):347-56. doi: 10.1016/s0006-2952(99)00346-9. Biochem Pharmacol. 2000. PMID: 10644042

3

2(1H)-quinolinone derivatives as novel anti-arteriostenotic agents showing anti-thrombotic and anti-hyperplastic activities.

Koga Y, Kihara Y, Okada M, Inoue Y, Tochizawa S, Toga K, Tachibana K, Kimura Y, Nishi T, Hidaka H. Koga Y, et al. Among authors: tachibana k. Bioorg Med Chem Lett. 1998 Jun 16;8(12):1471-6. doi: 10.1016/s0960-894x(98)00246-7. Bioorg Med Chem Lett. 1998. PMID: 9873372

4

Suppression of arterial intimal hyperplasia by cilostamide, a cyclic nucleotide phosphodiesterase 3 inhibitor, in a rat balloon double-injury model.

Inoue Y, Toga K, Sudo T, Tachibana K, Tochizawa S, Kimura Y, Yoshida Y, Hidaka H. Inoue Y, et al. Among authors: tachibana k. Br J Pharmacol. 2000 May;130(2):231-41. doi: 10.1038/sj.bjp.0703287. Br J Pharmacol. 2000. PMID: 10807659 Free PMC article.

5

Discovery of 7alpha-substituted dihydrotestosterones as androgen receptor pure antagonists and their structure-activity relationships.

Tachibana K, Imaoka I, Yoshino H, Emura T, Kodama H, Furuta Y, Kato N, Nakamura M, Ohta M, Taniguchi K, Ishikura N, Nagamuta M, Onuma E, Sato H. Tachibana K, et al. Bioorg Med Chem. 2007 Jan 1;15(1):174-85. doi: 10.1016/j.bmc.2006.09.072. Epub 2006 Oct 4. Bioorg Med Chem. 2007. PMID: 17064916

6

Structure-activity relationships of bioisosteric replacement of the carboxylic acid in novel androgen receptor pure antagonists.

Yoshino H, Sato H, Tachibana K, Shiraishi T, Nakamura M, Ohta M, Ishikura N, Nagamuta M, Onuma E, Nakagawa T, Arai S, Ahn KH, Jung KY, Kawata H. Yoshino H, et al. Among authors: tachibana k. Bioorg Med Chem. 2010 May 1;18(9):3159-68. doi: 10.1016/j.bmc.2010.03.036. Epub 2010 Mar 19. Bioorg Med Chem. 2010. PMID: 20381361

7

Design and synthesis of an androgen receptor pure antagonist (CH5137291) for the treatment of castration-resistant prostate cancer.

Yoshino H, Sato H, Shiraishi T, Tachibana K, Emura T, Honma A, Ishikura N, Tsunenari T, Watanabe M, Nishimoto A, Nakamura R, Nakagawa T, Ohta M, Takata N, Furumoto K, Kimura K, Kawata H. Yoshino H, et al. Among authors: tachibana k. Bioorg Med Chem. 2010 Dec 1;18(23):8150-7. doi: 10.1016/j.bmc.2010.10.023. Epub 2010 Oct 15. Bioorg Med Chem. 2010. PMID: 21050768

8

Discovery and structure-activity relationships of new steroidal compounds bearing a carboxy-terminal side chain as androgen receptor pure antagonists.

Tachibana K, Imaoka I, Yoshino H, Kato N, Nakamura M, Ohta M, Kawata H, Taniguchi K, Ishikura N, Nagamuta M, Onuma E, Sato H. Tachibana K, et al. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5573-6. doi: 10.1016/j.bmcl.2007.07.090. Epub 2007 Aug 22. Bioorg Med Chem Lett. 2007. PMID: 17804229

9

Efficient asymmetric synthesis of novel gastrin receptor antagonist AG-041R via highly stereoselective alkylation of oxindole enolates.

Emura T, Esaki T, Tachibana K, Shimizu M. Emura T, et al. Among authors: tachibana k. J Org Chem. 2006 Oct 27;71(22):8559-64. doi: 10.1021/jo061541v. J Org Chem. 2006. PMID: 17064034

10

Biological properties of androgen receptor pure antagonist for treatment of castration-resistant prostate cancer: optimization from lead compound to CH5137291.

Kawata H, Arai S, Nakagawa T, Ishikura N, Nishimoto A, Yoshino H, Shiraishi T, Tachibana K, Nakamura R, Sato H. Kawata H, et al. Among authors: tachibana k. Prostate. 2011 Sep;71(12):1344-56. doi: 10.1002/pros.21351. Epub 2011 Feb 9. Prostate. 2011. PMID: 21308717

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