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Characterization of placental bikunin, a novel human serine protease inhibitor.
Delaria KA, Muller DK, Marlor CW, Brown JE, Das RC, Roczniak SO, Tamburini PP. Delaria KA, et al. J Biol Chem. 1997 May 2;272(18):12209-14. doi: 10.1074/jbc.272.18.12209. J Biol Chem. 1997. PMID: 9115295 Free article.
We reported previously the cloning of a novel human serine protease inhibitor containing two Kunitz-like domains, designated as placental bikunin, and the subsequent purification of a natural counterpart from human placental tissue (Marlor, C. W., Delaria, K. A., Da …
We reported previously the cloning of a novel human serine protease inhibitor containing two Kunitz-like domains, designated as placental bi …
A T-cell-selective interleukin 2 mutein exhibits potent antitumor activity and is well tolerated in vivo.
Shanafelt AB, Lin Y, Shanafelt MC, Forte CP, Dubois-Stringfellow N, Carter C, Gibbons JA, Cheng SL, Delaria KA, Fleischer R, Greve JM, Gundel R, Harris K, Kelly R, Koh B, Li Y, Lantz L, Mak P, Neyer L, Plym MJ, Roczniak S, Serban D, Thrift J, Tsuchiyama L, Wetzel M, Wong M, Zolotorev A. Shanafelt AB, et al. Among authors: delaria ka. Nat Biotechnol. 2000 Nov;18(11):1197-202. doi: 10.1038/81199. Nat Biotechnol. 2000. PMID: 11062441
Effect of attachment site on stability of cleavable antibody drug conjugates.
Dorywalska M, Strop P, Melton-Witt JA, Hasa-Moreno A, Farias SE, Galindo Casas M, Delaria K, Lui V, Poulsen K, Loo C, Krimm S, Bolton G, Moine L, Dushin R, Tran TT, Liu SH, Rickert M, Foletti D, Shelton DL, Pons J, Rajpal A. Dorywalska M, et al. Among authors: delaria k. Bioconjug Chem. 2015 Apr 15;26(4):650-9. doi: 10.1021/bc5005747. Epub 2015 Feb 20. Bioconjug Chem. 2015. PMID: 25643134
Location matters: site of conjugation modulates stability and pharmacokinetics of antibody drug conjugates.
Strop P, Liu SH, Dorywalska M, Delaria K, Dushin RG, Tran TT, Ho WH, Farias S, Casas MG, Abdiche Y, Zhou D, Chandrasekaran R, Samain C, Loo C, Rossi A, Rickert M, Krimm S, Wong T, Chin SM, Yu J, Dilley J, Chaparro-Riggers J, Filzen GF, O'Donnell CJ, Wang F, Myers JS, Pons J, Shelton DL, Rajpal A. Strop P, et al. Among authors: delaria k. Chem Biol. 2013 Feb 21;20(2):161-7. doi: 10.1016/j.chembiol.2013.01.010. Chem Biol. 2013. PMID: 23438745
Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy.
Dorywalska M, Strop P, Melton-Witt JA, Hasa-Moreno A, Farias SE, Galindo Casas M, Delaria K, Lui V, Poulsen K, Sutton J, Bolton G, Zhou D, Moine L, Dushin R, Tran TT, Liu SH, Rickert M, Foletti D, Shelton DL, Pons J, Rajpal A. Dorywalska M, et al. Among authors: delaria k. PLoS One. 2015 Jul 10;10(7):e0132282. doi: 10.1371/journal.pone.0132282. eCollection 2015. PLoS One. 2015. PMID: 26161543 Free PMC article.
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