Akamizu T - Search Results

1

Chimeric studies of the extracellular domain of the rat thyrotropin (TSH) receptor: amino acids (268-304) in the TSH receptor are involved in ligand high affinity binding, but not in TSH receptor-specific signal transduction.

Akamizu T, Inoue D, Kosugi S, Ban T, Kohn LD, Imura H, Mori T. Akamizu T, et al. Endocr J. 1993 Jun;40(3):363-72. doi: 10.1507/endocrj.40.363. Endocr J. 1993. PMID: 7920890 Free article.

2

Molecular basis for the autoreactivity against thyroid stimulating hormone receptor.

Kohn LD, Kosugi S, Ban T, Saji M, Ikuyama S, Giuliani C, Hidaka A, Shimura H, Akamizu T, Tahara K, et al. Kohn LD, et al. Among authors: akamizu t. Int Rev Immunol. 1992;9(2):135-65. doi: 10.3109/08830189209061788. Int Rev Immunol. 1992. PMID: 1283175 Review.

3

Regulation of thyrotropin receptor gene expression in rat FRTL-5 thyroid cells.

Saji M, Akamizu T, Sanchez M, Obici S, Avvedimento E, Gottesman ME, Kohn LD. Saji M, et al. Among authors: akamizu t. Endocrinology. 1992 Jan;130(1):520-33. doi: 10.1210/endo.130.1.1309347. Endocrinology. 1992. PMID: 1309347

4

Characterization of the 5'-flanking region of the rat thyrotropin receptor gene.

Ikuyama S, Niller HH, Shimura H, Akamizu T, Kohn LD. Ikuyama S, et al. Among authors: akamizu t. Mol Endocrinol. 1992 May;6(5):793-804. doi: 10.1210/mend.6.5.1318504. Mol Endocrinol. 1992. PMID: 1318504

5

Opposite regulation of deoxyribonucleic acid synthesis and iodide uptake in rat thyroid cells by basic fibroblast growth factor: correlation with opposite regulation of c-fos and thyrotropin receptor gene expression.

Isozaki O, Emoto N, Tsushima T, Sato Y, Shizume K, Demura H, Akamizu T, Kohn LD. Isozaki O, et al. Among authors: akamizu t. Endocrinology. 1992 Dec;131(6):2723-32. doi: 10.1210/endo.131.6.1332847. Endocrinology. 1992. PMID: 1332847

6

Role of cysteine residues in the extracellular domain and exoplasmic loops of the transmembrane domain of the TSH receptor: effect of mutation to serine on TSH receptor activity and response to thyroid stimulating autoantibodies.

Kosugi S, Ban T, Akamizu T, Kohn LD. Kosugi S, et al. Among authors: akamizu t. Biochem Biophys Res Commun. 1992 Dec 30;189(3):1754-62. doi: 10.1016/0006-291x(92)90281-o. Biochem Biophys Res Commun. 1992. PMID: 1336379

7

Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid-stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxedema: these determinants have no homologous sequence on gonadotropin receptors.

Kosugi S, Ban T, Akamizu T, Kohn LD. Kosugi S, et al. Among authors: akamizu t. Mol Endocrinol. 1992 Feb;6(2):168-80. doi: 10.1210/mend.6.2.1349156. Mol Endocrinol. 1992. PMID: 1349156

8

Site-directed mutagenesis of a portion of the extracellular domain of the rat thyrotropin receptor important in autoimmune thyroid disease and nonhomologous with gonadotropin receptors. Relationship of functional and immunogenic domains.

Kosugi S, Ban T, Akamizu T, Kohn LD. Kosugi S, et al. Among authors: akamizu t. J Biol Chem. 1991 Oct 15;266(29):19413-8. J Biol Chem. 1991. PMID: 1655787 Free article.

9

Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies.

Akamizu T, Ikuyama S, Saji M, Kosugi S, Kozak C, McBride OW, Kohn LD. Akamizu T, et al. Proc Natl Acad Sci U S A. 1990 Aug;87(15):5677-81. doi: 10.1073/pnas.87.15.5677. Proc Natl Acad Sci U S A. 1990. PMID: 1696008 Free PMC article.

10

Thyrotropin receptor gene expression in oncogene-transfected rat thyroid cells: correlation between transformation, loss of thyrotropin-dependent growth, and loss of thyrotropin receptor gene expression.

Berlingieri MT, Akamizu T, Fusco A, Grieco M, Colletta G, Cirafici AM, Ikuyama S, Kohn LD, Vecchio G. Berlingieri MT, et al. Among authors: akamizu t. Biochem Biophys Res Commun. 1990 Nov 30;173(1):172-8. doi: 10.1016/s0006-291x(05)81037-x. Biochem Biophys Res Commun. 1990. PMID: 1701631

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