Begent RH - Search Results

1

Phage libraries for generation of clinically useful antibodies.

Chester KA, Begent RH, Robson L, Keep P, Pedley RB, Boden JA, Boxer G, Green A, Winter G, Cochet O, et al. Chester KA, et al. Among authors: begent rh. Lancet. 1994 Feb 19;343(8895):455-6. doi: 10.1016/s0140-6736(94)92695-6. Lancet. 1994. PMID: 7905958

2

Localisation of monoclonal antibodies reacting with different epitopes on carcinoembryonic antigen (CEA)--implications for targeted therapy.

Boxer GM, Abassi AM, Pedley RB, Begent RH. Boxer GM, et al. Among authors: begent rh. Br J Cancer. 1994 Feb;69(2):307-14. doi: 10.1038/bjc.1994.56. Br J Cancer. 1994. PMID: 7507692 Free PMC article.

3

A single chain Fv derived from a filamentous phage library has distinct tumor targeting advantages over one derived from a hybridoma.

Verhaar MJ, Chester KA, Keep PA, Robson L, Pedley RB, Boden JA, Hawkins RE, Begent RH. Verhaar MJ, et al. Among authors: begent rh. Int J Cancer. 1995 May 16;61(4):497-501. doi: 10.1002/ijc.2910610412. Int J Cancer. 1995. PMID: 7759155

4

Production and tumour-binding characterization of a chimeric anti-CEA Fab expressed in Escherichia coli.

Chester KA, Robson L, Keep PA, Pedley RB, Boden JA, Boxer GM, Hawkins RE, Begent RH. Chester KA, et al. Among authors: begent rh. Int J Cancer. 1994 Apr 1;57(1):67-72. doi: 10.1002/ijc.2910570113. Int J Cancer. 1994. PMID: 8150543

5

Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library.

Begent RH, Verhaar MJ, Chester KA, Casey JL, Green AJ, Napier MP, Hope-Stone LD, Cushen N, Keep PA, Johnson CJ, Hawkins RE, Hilson AJ, Robson L. Begent RH, et al. Nat Med. 1996 Sep;2(9):979-84. doi: 10.1038/nm0996-979. Nat Med. 1996. PMID: 8782454 Clinical Trial.

6

Taking engineered anti-CEA antibodies to the clinic.

Mayer A, Chester KA, Flynn AA, Begent RH. Mayer A, et al. Among authors: begent rh. J Immunol Methods. 1999 Dec 10;231(1-2):261-73. doi: 10.1016/s0022-1759(99)00162-3. J Immunol Methods. 1999. PMID: 10648943 Review.

7

Recombinant anti-carcinoembryonic antigen antibodies for targeting cancer.

Chester KA, Mayer A, Bhatia J, Robson L, Spencer DI, Cooke SP, Flynn AA, Sharma SK, Boxer G, Pedley RB, Begent RH. Chester KA, et al. Among authors: begent rh. Cancer Chemother Pharmacol. 2000;46 Suppl:S8-12. doi: 10.1007/pl00014055. Cancer Chemother Pharmacol. 2000. PMID: 10950140 Review.

8

Enhanced tumour specificity of an anti-carcinoembrionic antigen Fab' fragment by poly(ethylene glycol) (PEG) modification.

Delgado C, Pedley RB, Herraez A, Boden R, Boden JA, Keep PA, Chester KA, Fisher D, Begent RH, Francis GE. Delgado C, et al. Among authors: begent rh. Br J Cancer. 1996 Jan;73(2):175-82. doi: 10.1038/bjc.1996.32. Br J Cancer. 1996. PMID: 8546903 Free PMC article.

9

Factors influencing variability of localisation of antibodies to carcinoembryonic antigen (CEA) in patients with colorectal carcinoma--implications for radioimmunotherapy.

Boxer GM, Begent RH, Kelly AM, Southall PJ, Blair SB, Theodorou NA, Dawson PM, Ledermann JA. Boxer GM, et al. Among authors: begent rh. Br J Cancer. 1992 Jun;65(6):825-31. doi: 10.1038/bjc.1992.176. Br J Cancer. 1992. PMID: 1616854 Free PMC article.

10

The effect of radiosensitizers on radio-immunotherapy, using 131I-labelled anti-CEA antibodies in a human colonic xenograft model.

Pedley RB, Begent RH, Boden JA, Boden R, Adam T, Bagshawe KD. Pedley RB, et al. Among authors: begent rh. Int J Cancer. 1991 Feb 20;47(4):597-602. doi: 10.1002/ijc.2910470420. Int J Cancer. 1991. PMID: 1995488

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