Conformational requirement of signal sequences functioning in yeast: circular dichroism and 1H nuclear magnetic resonance studies of synthetic peptides.
Yamamoto Y, Ohkubo T, Kohara A, Tanaka T, Tanaka T, Kikuchi M.
Yamamoto Y, et al.
Biochemistry. 1990 Sep 25;29(38):8998-9006. doi: 10.1021/bi00490a017.
Biochemistry. 1990.
PMID: 2271573
Recently, we have designed a series of simplified artificial signal sequences and have shown that a proline residue in the signal sequence plays an important role in the secretion of human lysozyme in yeast, presumably by altering the conformation of the signal sequence [Yamam …
Recently, we have designed a series of simplified artificial signal sequences and have shown that a proline residue in the signal sequence p …