Den Besten C - Search Results

1

Immune effects of hexachlorobenzene in the rat: role of metabolism in a 13-week feeding study.

Schielen P, Den Besten C, Vos JG, Van Bladeren PJ, Seinen W, Bloksma N. Schielen P, et al. Among authors: den besten c. Toxicol Appl Pharmacol. 1995 Mar;131(1):37-43. doi: 10.1006/taap.1995.1044. Toxicol Appl Pharmacol. 1995. PMID: 7878676

2

Metabolic activation of 1,2,4-trichlorobenzene and pentachlorobenzene by rat liver microsomes: a major role for quinone metabolites.

den Besten C, Smink MC, de Vries EJ, van Bladeren PJ. den Besten C, et al. Toxicol Appl Pharmacol. 1991 Apr;108(2):223-33. doi: 10.1016/0041-008x(91)90113-s. Toxicol Appl Pharmacol. 1991. PMID: 2017752

3

The role of oxidative metabolism in hexachlorobenzene-induced porphyria and thyroid hormone homeostasis: a comparison with pentachlorobenzene in a 13-week feeding study.

den Besten C, Bennik MH, Bruggeman I, Schielen P, Kuper F, Brouwer A, Koeman JH, Vos JG, Van Bladeren PJ. den Besten C, et al. Toxicol Appl Pharmacol. 1993 Apr;119(2):181-94. doi: 10.1006/taap.1993.1059. Toxicol Appl Pharmacol. 1993. PMID: 8480328

4

Comparative biotransformation of hexachlorobenzene and hexafluorobenzene in relation to the induction of porphyria.

Rietjens IM, Steensma A, Den Besten C, van Tintelen G, Haas J, van Ommen B, van Bladeren PJ. Rietjens IM, et al. Among authors: den besten c. Eur J Pharmacol. 1995 Dec 7;293(4):293-9. doi: 10.1016/0926-6917(95)90048-9. Eur J Pharmacol. 1995. PMID: 8748681

5

The liver, kidney, and thyroid toxicity of chlorinated benzenes.

den Besten C, Vet JJ, Besselink HT, Kiel GS, van Berkel BJ, Beems R, van Bladeren PJ. den Besten C, et al. Toxicol Appl Pharmacol. 1991 Oct;111(1):69-81. doi: 10.1016/0041-008x(91)90135-2. Toxicol Appl Pharmacol. 1991. PMID: 1949037

6

The metabolism of pentachlorobenzene by rat liver microsomes: the nature of the reactive intermediates formed.

den Besten C, Peters MM, van Bladeren PJ. den Besten C, et al. Biochem Biophys Res Commun. 1989 Sep 29;163(3):1275-81. doi: 10.1016/0006-291x(89)91116-9. Biochem Biophys Res Commun. 1989. PMID: 2675838

7

Biotransformation and toxicity of halogenated benzenes.

den Besten C, Brouwer A, Rietjens IM, van Bladeren PJ. den Besten C, et al. Hum Exp Toxicol. 1994 Dec;13(12):866-75. doi: 10.1177/096032719401301209. Hum Exp Toxicol. 1994. PMID: 7718307 Review.

8

Comparison of the urinary metabolite profiles of hexachlorobenzene and pentachlorobenzene in the rat.

den Besten C, Bennik MM, van Iersel M, Peters MA, Teunis C, van Bladeren PJ. den Besten C, et al. Chem Biol Interact. 1994 Feb;90(2):121-37. doi: 10.1016/0009-2797(94)90098-1. Chem Biol Interact. 1994. PMID: 8156603

9

Cytochrome P450-catalyzed oxidation of halobenzene derivatives.

Rietjens IM, den Besten C, Hanzlik RP, van Bladeren PJ. Rietjens IM, et al. Among authors: den besten c. Chem Res Toxicol. 1997 Jun;10(6):629-35. doi: 10.1021/tx9601061. Chem Res Toxicol. 1997. PMID: 9208168 Review. No abstract available.

10

Cytochrome P450-mediated oxidation of pentafluorophenol to tetrafluorobenzoquinone as the primary reaction product.

den Besten C, van Bladeren PJ, Duizer E, Vervoort J, Rietjens IM. den Besten C, et al. Chem Res Toxicol. 1993 Sep-Oct;6(5):674-80. doi: 10.1021/tx00035a013. Chem Res Toxicol. 1993. PMID: 8292746

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