Spinelli S - Search Results

1

Chromophore-modified antitumor anthracenediones: synthesis, DNA binding, and cytotoxic activity of 1,4-bis[(aminoalkyl)amino]benzo[g]-phthalazine-5,10-diones.

Gandolfi CA, Beggiolin G, Menta E, Palumbo M, Sissi C, Spinelli S, Johnson F. Gandolfi CA, et al. Among authors: spinelli s. J Med Chem. 1995 Feb 3;38(3):526-36. doi: 10.1021/jm00003a015. J Med Chem. 1995. PMID: 7853345

2

N-acyl-2-substituted-1,3-thiazolidines, a new class of non-narcotic antitussive agents: studies leading to the discovery of ethyl 2-[(2-methoxyphenoxy)methyl]-beta-oxothiazolidine-3-propanoate.

Gandolfi CA, Di Domenico R, Spinelli S, Gallico L, Fiocchi L, Lotto A, Menta E, Borghi A, Dalla Rosa C, Tognella S. Gandolfi CA, et al. Among authors: spinelli s. J Med Chem. 1995 Feb 3;38(3):508-25. doi: 10.1021/jm00003a014. J Med Chem. 1995. PMID: 7853344

3

Topoisomerase II DNA cleavage stimulation, DNA binding activity, cytotoxicity, and physico-chemical properties of 2-aza- and 2-aza-oxide-anthracenedione derivatives.

De Isabella P, Palumbo M, Sissi C, Capranico G, Carenini N, Menta E, Oliva A, Spinelli S, Krapcho AP, Giuliani FC, et al. De Isabella P, et al. Among authors: spinelli s. Mol Pharmacol. 1995 Jul;48(1):30-8. Mol Pharmacol. 1995. PMID: 7623772

4

Synthesis and antitumor activity of a new class of pyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepinone analogues of pyrrolo[1,4][2,1-c]benzodiazepines.

Baraldi PG, Leoni A, Cacciari B, Manfredini S, Simoni D, Bergomi M, Menta E, Spinelli S. Baraldi PG, et al. Among authors: spinelli s. J Med Chem. 1994 Dec 9;37(25):4329-37. doi: 10.1021/jm00051a009. J Med Chem. 1994. PMID: 7996544

5

Physicochemical properties, cytotoxic activity and topoisomerase II inhibition of 2,3-diaza-anthracenediones.

de Isabella P, Palumbo M, Sissi C, Carenini N, Capranico G, Menta E, Oliva A, Spinelli S, Krapcho AP, Giuliani FC, Zunino F. de Isabella P, et al. Among authors: spinelli s. Biochem Pharmacol. 1997 Jan 24;53(2):161-9. doi: 10.1016/s0006-2952(96)00646-6. Biochem Pharmacol. 1997. PMID: 9037248

6

Synthesis and antitumor evaluation of 2,5-disubstituted-indazolo[4, 3-gh]isoquinolin-6(2H)-ones (9-aza-anthrapyrazoles).

Krapcho AP, Menta E, Oliva A, Di Domenico R, Fiocchi L, Maresch ME, Gallagher CE, Hacker MP, Beggiolin G, Giuliani FC, Pezzoni G, Spinelli S. Krapcho AP, et al. Among authors: spinelli s. J Med Chem. 1998 Dec 31;41(27):5429-44. doi: 10.1021/jm9804432. J Med Chem. 1998. PMID: 9876113

7

DNA-interactive anticancer aza-anthrapyrazoles: biophysical and biochemical studies relevant to the mechanism of action.

Sissi C, Moro S, Richter S, Gatto B, Menta E, Spinelli S, Krapcho AP, Zunino F, Palumbo M. Sissi C, et al. Among authors: spinelli s. Mol Pharmacol. 2001 Jan;59(1):96-103. doi: 10.1124/mol.59.1.96. Mol Pharmacol. 2001. PMID: 11125029

8

Bbr 2778, an aza-anthracenedione endowed with preclinical anticancer activity and lack of delayed cardiotoxicity.

Beggiolin G, Crippa L, Menta E, Manzotti C, Cavalletti E, Pezzoni G, Torriani D, Randisi E, Cavagnoli R, Sala F, Giuliani FC, Spinelli S. Beggiolin G, et al. Among authors: spinelli s. Tumori. 2001 Nov-Dec;87(6):407-16. doi: 10.1177/030089160108700611. Tumori. 2001. PMID: 11989596

9

Aza and diaza bioisosteric anthracene-9,10-diones as antitumor agents.

Krapcho AP, Maresch MJ, Hacker MP, Menta E, Oliva A, Giuliani FC, Spinelli S. Krapcho AP, et al. Among authors: spinelli s. Acta Biochim Pol. 1995;42(4):427-32. Acta Biochim Pol. 1995. PMID: 8852333 Review.

10

Cytotoxicity evaluation of natural coptisine and synthesis of coptisine from berberine.

Colombo ML, Bugatti C, Mossa A, Pescalli N, Piazzoni L, Pezzoni G, Menta E, Spinelli S, Johnson F, Gupta RC, Dasaradhi L. Colombo ML, et al. Among authors: spinelli s. Farmaco. 2001 May-Jul;56(5-7):403-9. doi: 10.1016/s0014-827x(01)01121-1. Farmaco. 2001. PMID: 11482767

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