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Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome.
Matico R, Grauwen K, Chauhan D, Yu X, Abdiaj I, Adhikary S, Adriaensen I, Aranzazu GM, Alcázar J, Bassi M, Brisse E, Cañellas S, Chaudhuri S, Delgado F, Diéguez-Vázquez A, Du Jardin M, Eastham V, Finley M, Jacobs T, Keustermans K, Kuhn R, Llaveria J, Leenaerts J, Linares ML, Martín ML, Martín-Pérez R, Martínez C, Miller R, Muñoz FM, Muratore ME, Nooyens A, Perez-Benito L, Perrier M, Pietrak B, Serré J, Sharma S, Somers M, Suarez J, Tresadern G, Trabanco AA, Van den Bulck D, Van Gool M, Van Hauwermeiren F, Varghese T, Vega JA, Youssef SA, Edwards MJ, Oehlrich D, Van Opdenbosch N. Matico R, et al. Among authors: kuhn r. EMBO Mol Med. 2024 Dec 9. doi: 10.1038/s44321-024-00181-4. Online ahead of print. EMBO Mol Med. 2024. PMID: 39653810 Free article.
Flavivirus NS1-triggered endothelial dysfunction promotes virus dissemination.
Puerta-Guardo H, Biering SB, Castillo-Rojas B, DiBiasio-White MJ, Lo NT, Espinosa DA, Warnes CM, Wang C, Cao T, Glasner DR, Beatty PR, Kuhn RJ, Harris E. Puerta-Guardo H, et al. Among authors: kuhn rj. bioRxiv [Preprint]. 2024 Nov 30:2024.11.29.625931. doi: 10.1101/2024.11.29.625931. bioRxiv. 2024. PMID: 39651279 Free PMC article. Preprint.
1,426 results