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Butenolide endothelin antagonists with improved aqueous solubility.
Patt WC, Cheng XM, Repine JT, Lee C, Reisdorph BR, Massa MA, Doherty AM, Welch KM, Bryant JW, Flynn MA, Walker DM, Schroeder RL, Haleen SJ, Keiser JA. Patt WC, et al. Among authors: keiser ja. J Med Chem. 1999 Jun 17;42(12):2162-8. doi: 10.1021/jm980504w. J Med Chem. 1999. PMID: 10377221
Why big endothelin-1 lacks a vasodilator response.
Haleen SJ, Davis LS, LaDouceur DM, Keiser JA. Haleen SJ, et al. Among authors: keiser ja. J Cardiovasc Pharmacol. 1993;22 Suppl 8:S271-3. doi: 10.1097/00005344-199322008-00071. J Cardiovasc Pharmacol. 1993. PMID: 7509963
68 results