Ghai RD - Search Results

1

Dicarboxylic acid dipeptide neutral endopeptidase inhibitors.

Ksander GM, Ghai RD, deJesus R, Diefenbacher CG, Yuan A, Berry C, Sakane Y, Trapani A. Ksander GM, et al. Among authors: ghai rd. J Med Chem. 1995 May 12;38(10):1689-700. doi: 10.1021/jm00010a014. J Med Chem. 1995. PMID: 7752193

2

Characterisation of neutral endopeptidase 3.4.24.11 (NEP) in the kidney: comparison between normotensive, genetically hypertensive and experimentally hypertensive rats.

Schulz R, Sakane Y, Berry C, Ghai R. Schulz R, et al. J Enzyme Inhib. 1991;4(4):347-58. doi: 10.3109/14756369109030399. J Enzyme Inhib. 1991. PMID: 1669834

3

Enkephalinase inhibitors. 1. 2,4-Dibenzylglutaric acid derivatives.

Ksander GM, Diefenbacher CG, Yuan AM, Clark F, Sakane Y, Ghai RD. Ksander GM, et al. Among authors: ghai rd. J Med Chem. 1989 Dec;32(12):2519-26. doi: 10.1021/jm00132a005. J Med Chem. 1989. PMID: 2585440

4

A rapid indirect method to determine the plasma concentrations of neutral endopeptidase inhibitors.

Ghai RD, De Lombaert S, Ksander GM, Berry C, Sakane Y, Trapani AJ. Ghai RD, et al. Res Commun Mol Pathol Pharmacol. 1995 Feb;87(2):211-20. Res Commun Mol Pathol Pharmacol. 1995. PMID: 7749658

5

Pharmacological profile of a non-peptidic dual inhibitor of neutral endopeptidase 24.11 and endothelin-converting enzyme.

De Lombaert S, Ghai RD, Jeng AY, Trapani AJ, Webb RL. De Lombaert S, et al. Among authors: ghai rd. Biochem Biophys Res Commun. 1994 Oct 14;204(1):407-12. doi: 10.1006/bbrc.1994.2473. Biochem Biophys Res Commun. 1994. PMID: 7945387

6

N-Phosphonomethyl dipeptides and their phosphonate prodrugs, a new generation of neutral endopeptidase (NEP, EC 3.4.24.11) inhibitors.

De Lombaert S, Erion MD, Tan J, Blanchard L, el-Chehabi L, Ghai RD, Sakane Y, Berry C, Trapani AJ. De Lombaert S, et al. Among authors: ghai rd. J Med Chem. 1994 Feb 18;37(4):498-511. doi: 10.1021/jm00030a009. J Med Chem. 1994. PMID: 8120868

7

Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor.

MacPherson LJ, Bayburt EK, Capparelli MP, Bohacek RS, Clarke FH, Ghai RD, Sakane Y, Berry CJ, Peppard JV, Trapani AJ. MacPherson LJ, et al. Among authors: ghai rd. J Med Chem. 1993 Nov 26;36(24):3821-8. doi: 10.1021/jm00076a009. J Med Chem. 1993. PMID: 8254611

8

Heterocyclic lactam derivatives as dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibitors.

Stanton JL, Sperbeck DM, Trapani AJ, Cote D, Sakane Y, Berry CJ, Ghai RD. Stanton JL, et al. Among authors: ghai rd. J Med Chem. 1993 Nov 26;36(24):3829-33. doi: 10.1021/jm00076a010. J Med Chem. 1993. PMID: 8254612

9

New alpha-thiol dipeptide dual inhibitors of angiotensin-I converting enzyme and neutral endopeptidase EC 3.4.24.11.

Fink CA, Qiao Y, Berry CJ, Sakane Y, Ghai RD, Trapani AJ. Fink CA, et al. Among authors: ghai rd. J Med Chem. 1995 Dec 22;38(26):5023-30. doi: 10.1021/jm00026a009. J Med Chem. 1995. PMID: 8544178

10

Ortho-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors.

Ksander GM, de Jesus R, Yuan A, Ghai RD, Trapani A, McMartin C, Bohacek R. Ksander GM, et al. Among authors: ghai rd. J Med Chem. 1997 Feb 14;40(4):495-505. doi: 10.1021/jm960582o. J Med Chem. 1997. PMID: 9046340

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