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Structural studies on bioactive compounds. Part 27. Chemistry of the immunomodulatory agent bropirimine.
Anticancer Drug Des. 1995 Apr;10(3):215-26.
Anticancer Drug Des. 1995.
PMID: 7748456
Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine.
Stevens MF, Hickman JA, Langdon SP, Chubb D, Vickers L, Stone R, Baig G, Goddard C, Gibson NW, Slack JA, et al.
Stevens MF, et al.
Cancer Res. 1987 Nov 15;47(22):5846-52.
Cancer Res. 1987.
PMID: 3664486
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Antitumor imidazotetrazines. 20. Preparation of the 8-acid derivative of mitozolomide and its utility in the preparation of active antitumor agents.
Horspool KR, Stevens MF, Newton CG, Lunt E, Walsh RJ, Pedgrift BL, Baig GU, Lavelle F, Fizames C.
Horspool KR, et al. Among authors: baig gu.
J Med Chem. 1990 May;33(5):1393-9. doi: 10.1021/jm00167a018.
J Med Chem. 1990.
PMID: 2329560
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Antitumor imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one , a novel broad-spectrum antitumor agent.
Stevens MF, Hickman JA, Stone R, Gibson NW, Baig GU, Lunt E, Newton CG.
Stevens MF, et al. Among authors: baig gu.
J Med Chem. 1984 Feb;27(2):196-201. doi: 10.1021/jm00368a016.
J Med Chem. 1984.
PMID: 6694168
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