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Dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA), two naturally occurring benzoxazinones contained in sprouts of Gramineae are potent aneugens in human-derived liver cells (HepG2).
Buchmann CA, Nersesyan A, Kopp B, Schauberger D, Darroudi F, Grummt T, Krupitza G, Kundi M, Schulte-Hermann R, Knasmueller S. Buchmann CA, et al. Among authors: kundi m. Cancer Lett. 2007 Feb 8;246(1-2):290-9. doi: 10.1016/j.canlet.2006.03.013. Epub 2006 Apr 27. Cancer Lett. 2007. PMID: 16644106
Recommendations and quality criteria for micronucleus studies with humans.
Nersesyan A, Kundi M, Fenech M, Stopper H, da Silva J, Bolognesi C, Mišík M, Knasmueller S. Nersesyan A, et al. Among authors: kundi m. Mutat Res Rev Mutat Res. 2022 Jan-Jun;789:108410. doi: 10.1016/j.mrrev.2021.108410. Epub 2021 Dec 20. Mutat Res Rev Mutat Res. 2022. PMID: 35690413 Review.
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