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Page 1
From anesthetic mechanisms research to drug discovery.
Eckenhoff R, Zheng W, Kelz M. Eckenhoff R, et al. Clin Pharmacol Ther. 2008 Jul;84(1):144-8. doi: 10.1038/clpt.2008.77. Epub 2008 Apr 30. Clin Pharmacol Ther. 2008. PMID: 18449184 Review.
One to rule them all?
Terrando N, Eckenhoff RG. Terrando N, et al. Among authors: eckenhoff rg. Br J Anaesth. 2018 Mar;120(3):428-430. doi: 10.1016/j.bja.2017.12.006. Epub 2018 Jan 17. Br J Anaesth. 2018. PMID: 29452796 Free article. No abstract available.
Propofol binds and inhibits skeletal muscle ryanodine receptor 1.
Joseph TT, Bu W, Haji-Ghassemi O, Chen YS, Woll K, Allen PD, Brannigan G, van Petegem F, Eckenhoff RG. Joseph TT, et al. Among authors: eckenhoff rg. Br J Anaesth. 2024 Nov;133(5):1093-1100. doi: 10.1016/j.bja.2024.06.048. Epub 2024 Sep 19. Br J Anaesth. 2024. PMID: 39304470 Free PMC article.
Dexmedetomidine directly binds to and inhibits Toll-like receptor 4.
Koutsogiannaki S, Limratana P, Bu W, Maisat W, McKinstry-Wu A, Han X, Ohto U, Eckenhoff RG, Soriano SG, Yuki K. Koutsogiannaki S, et al. Among authors: eckenhoff rg. Int Immunopharmacol. 2024 Nov 15;141:112975. doi: 10.1016/j.intimp.2024.112975. Epub 2024 Aug 19. Int Immunopharmacol. 2024. PMID: 39163686
Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1).
Joseph TT, Bu W, Haji-Ghassemi O, Chen YS, Woll K, Allen PD, Brannigan G, van Petegem F, Eckenhoff RG. Joseph TT, et al. Among authors: eckenhoff rg. bioRxiv [Preprint]. 2024 Jan 12:2024.01.10.575040. doi: 10.1101/2024.01.10.575040. bioRxiv. 2024. Update in: Br J Anaesth. 2024 Nov;133(5):1093-1100. doi: 10.1016/j.bja.2024.06.048 PMID: 38260485 Free PMC article. Updated. Preprint.
213 results