Rooney CS - Search Results

1

Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one.

Wai JS, Williams TM, Bamberger DL, Fisher TE, Hoffman JM, Hudcosky RJ, MacTough SC, Rooney CS, Saari WS, Thomas CM, et al. Wai JS, et al. Among authors: rooney cs. J Med Chem. 1993 Jan 22;36(2):249-55. doi: 10.1021/jm00054a009. J Med Chem. 1993. PMID: 7678654

2

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogues of 3-aminopyridin-2(1H)-one.

Saari WS, Wai JS, Fisher TE, Thomas CM, Hoffman JM, Rooney CS, Smith AM, Jones JH, Bamberger DL, Goldman ME, et al. Saari WS, et al. Among authors: rooney cs. J Med Chem. 1992 Oct 16;35(21):3792-802. doi: 10.1021/jm00099a007. J Med Chem. 1992. PMID: 1279173

3

2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors.

Saari WS, Hoffman JM, Wai JS, Fisher TE, Rooney CS, Smith AM, Thomas CM, Goldman ME, O'Brien JA, Nunberg JH, et al. Saari WS, et al. Among authors: rooney cs. J Med Chem. 1991 Sep;34(9):2922-5. doi: 10.1021/jm00113a036. J Med Chem. 1991. PMID: 1716683 No abstract available.

4

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogues.

Hoffman JM, Smith AM, Rooney CS, Fisher TE, Wai JS, Thomas CM, Bamberger DL, Barnes JL, Williams TM, Jones JH, et al. Hoffman JM, et al. Among authors: rooney cs. J Med Chem. 1993 Apr 16;36(8):953-66. doi: 10.1021/jm00060a002. J Med Chem. 1993. PMID: 7683054

5

5-chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase.

Williams TM, Ciccarone TM, MacTough SC, Rooney CS, Balani SK, Condra JH, Emini EA, Goldman ME, Greenlee WJ, Kauffman LR, et al. Williams TM, et al. Among authors: rooney cs. J Med Chem. 1993 Apr 30;36(9):1291-4. doi: 10.1021/jm00061a022. J Med Chem. 1993. PMID: 7683725

6

Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.

Balani SK, Pitzenberger SM, Kauffman LR, Arison BH, Ramjit HG, Goldman ME, O'Brien JA, King JD, Hoffman JM, Rooney CS, et al. Balani SK, et al. Among authors: rooney cs. Drug Metab Dispos. 1992 Nov-Dec;20(6):869-76. Drug Metab Dispos. 1992. PMID: 1283569

7

Metabolism of 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2 (1H)-one (L-696,229), an HIV-1 reverse transcriptase inhibitor, by rat liver slices and in humans.

Balani SK, Kauffman LR, Arison BH, Olah TV, Goldman ME, Varga SL, O'Brien JA, Ramjit HG, Rooney CS, Hoffman JM, et al. Balani SK, et al. Among authors: rooney cs. Drug Metab Dispos. 1994 Mar-Apr;22(2):200-5. Drug Metab Dispos. 1994. PMID: 7516852

8

Inhibitors of glycolic acid oxidase. 4-Substituted 3-hydroxy-1H-pyrrole-2,5-dione derivatives.

Rooney CS, Randall WC, Streeter KB, Ziegler C, Cragoe EJ Jr, Schwam H, Michelson SR, Williams HW, Eichler E, Duggan DE, Ulm EH, Noll RM. Rooney CS, et al. J Med Chem. 1983 May;26(5):700-14. doi: 10.1021/jm00359a015. J Med Chem. 1983. PMID: 6341589

9

Inhibitors of glycolic acid oxidase. 4-substituted 2,4-dioxobutanoic acid derivatives.

Williams HW, Eichler E, Randall WC, Rooney CS, Cragoe EJ Jr, Streeter KB, Schwam H, Michelson SR, Patchett AA, Taub D. Williams HW, et al. Among authors: rooney cs. J Med Chem. 1983 Aug;26(8):1196-200. doi: 10.1021/jm00362a020. J Med Chem. 1983. PMID: 6348285

10

Cyclic amidine inhibitors of indolamine N-methyltransferase.

Rokach J, Hamel P, Hunter NR, Reader G, Rooney CS, Anderson PS, Cragoe EJ Jr, Mandel LR. Rokach J, et al. Among authors: rooney cs. J Med Chem. 1979 Mar;22(3):237-47. doi: 10.1021/jm00189a004. J Med Chem. 1979. PMID: 423205

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