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Carboxyl end-specific monoclonal antibodies to amyloid beta protein (A beta) subtypes (A beta 40 and A beta 42(43)) differentiate A beta in senile plaques and amyloid angiopathy in brains of aged cynomolgus monkeys.
Nakamura S, Tamaoka A, Sawamura N, Shoji S, Nakayama H, Ono F, Sakakibara I, Yoshikawa Y, Mori H, Goto N, et al. Nakamura S, et al. Among authors: sawamura n. Neurosci Lett. 1995 Dec 8;201(2):151-4. doi: 10.1016/0304-3940(95)12160-9. Neurosci Lett. 1995. PMID: 8848240
Mutant presenilin 2 transgenic mouse: effect on an age-dependent increase of amyloid beta-protein 42 in the brain.
Oyama F, Sawamura N, Kobayashi K, Morishima-Kawashima M, Kuramochi T, Ito M, Tomita T, Maruyama K, Saido TC, Iwatsubo T, Capell A, Walter J, Grünberg J, Ueyama Y, Haass C, Ihara Y. Oyama F, et al. Among authors: sawamura n. J Neurochem. 1998 Jul;71(1):313-22. doi: 10.1046/j.1471-4159.1998.71010313.x. J Neurochem. 1998. PMID: 9648880 Free article.
Amyloid beta-protein affects cholesterol metabolism in cultured neurons: implications for pivotal role of cholesterol in the amyloid cascade.
Gong JS, Sawamura N, Zou K, Sakai J, Yanagisawa K, Michikawa M. Gong JS, et al. Among authors: sawamura n. J Neurosci Res. 2002 Nov 1;70(3):438-46. doi: 10.1002/jnr.10347. J Neurosci Res. 2002. PMID: 12391604
Recently, we have found that alterations in cellular cholesterol metabolism are involved in promotion of tau phosphorylation (Fan et al. [2001] J. Neurochem. 76: 391-400; Sawamura et al. [2001] J. Biol. Chem. 276:10314-10319). In addition, we have shown that amyloid beta-p …
Recently, we have found that alterations in cellular cholesterol metabolism are involved in promotion of tau phosphorylation (Fan et al. [20 …
78 results