Gonzalez C - Search Results

1

Chemical modification of hammerhead ribozymes. Catalytic activity and nuclease resistance.

Beigelman L, McSwiggen JA, Draper KG, Gonzalez C, Jensen K, Karpeisky AM, Modak AS, Matulic-Adamic J, DiRenzo AB, Haeberli P, et al. Beigelman L, et al. Among authors: gonzalez c. J Biol Chem. 1995 Oct 27;270(43):25702-8. doi: 10.1074/jbc.270.43.25702. J Biol Chem. 1995. PMID: 7592749 Free article.

2

Optimizing the cell efficacy of synthetic ribozymes. Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb.

Jarvis TC, Wincott FE, Alby LJ, McSwiggen JA, Beigelman L, Gustofson J, DiRenzo A, Levy K, Arthur M, Matulic-Adamic J, Karpeisky A, Gonzalez C, Woolf TM, Usman N, Stinchcomb DT. Jarvis TC, et al. Among authors: gonzalez c. J Biol Chem. 1996 Nov 15;271(46):29107-12. doi: 10.1074/jbc.271.46.29107. J Biol Chem. 1996. PMID: 8910566 Free article.

3

Chemically modified hammerhead ribozymes with improved catalytic rates.

Burgin AB Jr, Gonzalez C, Matulic-Adamic J, Karpeisky AM, Usman N, McSwiggen JA, Beigelman L. Burgin AB Jr, et al. Among authors: gonzalez c. Biochemistry. 1996 Nov 12;35(45):14090-7. doi: 10.1021/bi961264u. Biochemistry. 1996. PMID: 8916894

4

Nuclease resistant hammerhead motif: from '5-ribo' to '3-ribo' model.

Matulic-Adamic J, Daniher AT, Gonzalez C, Beigelman L. Matulic-Adamic J, et al. Among authors: gonzalez c. Bioorg Med Chem Lett. 1999 Jan 18;9(2):157-60. doi: 10.1016/s0960-894x(98)00706-9. Bioorg Med Chem Lett. 1999. PMID: 10021919

5

Synthesis, deprotection, analysis and purification of RNA and ribozymes.

Wincott F, DiRenzo A, Shaffer C, Grimm S, Tracz D, Workman C, Sweedler D, Gonzalez C, Scaringe S, Usman N. Wincott F, et al. Among authors: gonzalez c. Nucleic Acids Res. 1995 Jul 25;23(14):2677-84. doi: 10.1093/nar/23.14.2677. Nucleic Acids Res. 1995. PMID: 7544462 Free PMC article.

6

Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection.

Hoke GD, Draper K, Freier SM, Gonzalez C, Driver VB, Zounes MC, Ecker DJ. Hoke GD, et al. Among authors: gonzalez c. Nucleic Acids Res. 1991 Oct 25;19(20):5743-8. doi: 10.1093/nar/19.20.5743. Nucleic Acids Res. 1991. PMID: 1658742 Free PMC article.

7

Evaluation of 2'-modified oligonucleotides containing 2'-deoxy gaps as antisense inhibitors of gene expression.

Monia BP, Lesnik EA, Gonzalez C, Lima WF, McGee D, Guinosso CJ, Kawasaki AM, Cook PD, Freier SM. Monia BP, et al. Among authors: gonzalez c. J Biol Chem. 1993 Jul 5;268(19):14514-22. J Biol Chem. 1993. PMID: 8390996 Free article.

8

Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets.

Kawasaki AM, Casper MD, Freier SM, Lesnik EA, Zounes MC, Cummins LL, Gonzalez C, Cook PD. Kawasaki AM, et al. Among authors: gonzalez c. J Med Chem. 1993 Apr 2;36(7):831-41. doi: 10.1021/jm00059a007. J Med Chem. 1993. PMID: 8464037

9

Antisense oligodeoxynucleotides: synthesis, biophysical and biological evaluation of oligodeoxynucleotides containing modified pyrimidines.

Sanghvi YS, Hoke GD, Freier SM, Zounes MC, Gonzalez C, Cummins L, Sasmor H, Cook PD. Sanghvi YS, et al. Among authors: gonzalez c. Nucleic Acids Res. 1993 Jul 11;21(14):3197-203. doi: 10.1093/nar/21.14.3197. Nucleic Acids Res. 1993. PMID: 8393563 Free PMC article.

10

Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase by nuclear variants of mycophenolic acid.

Nelson PH, Carr SF, Devens BH, Eugui EM, Franco F, Gonzalez C, Hawley RC, Loughhead DG, Milan DJ, Papp E, Patterson JW, Rouhafza S, Sjogren EB, Smith DB, Stephenson RA, Talamas FX, Waltos AM, Weikert RJ, Wu JC. Nelson PH, et al. Among authors: gonzalez c. J Med Chem. 1996 Oct 11;39(21):4181-96. doi: 10.1021/jm9603633. J Med Chem. 1996. PMID: 8863796

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