Gorden P - Search Results

1

Receptor-mediated internalization of insulin. Potential role of pp120/HA4, a substrate of the insulin receptor kinase.

Formisano P, Najjar SM, Gross CN, Philippe N, Oriente F, Kern-Buell CL, Accili D, Gorden P. Formisano P, et al. Among authors: gorden p. J Biol Chem. 1995 Oct 13;270(41):24073-7. doi: 10.1074/jbc.270.41.24073. J Biol Chem. 1995. PMID: 7592607 Free article.

2

A novel human insulin receptor gene mutation uniquely inhibits insulin binding without impairing posttranslational processing.

Roach P, Zick Y, Formisano P, Accili D, Taylor SI, Gorden P. Roach P, et al. Among authors: gorden p. Diabetes. 1994 Sep;43(9):1096-102. doi: 10.2337/diab.43.9.1096. Diabetes. 1994. PMID: 8070609

3

Syndromes of autoimmunity and hypoglycemia. Autoantibodies directed against insulin and its receptor.

Taylor SI, Barbetti F, Accili D, Roth J, Gorden P. Taylor SI, et al. Among authors: gorden p. Endocrinol Metab Clin North Am. 1989 Mar;18(1):123-43. Endocrinol Metab Clin North Am. 1989. PMID: 2645123 Review.

4

Rescue and activation of a binding-deficient insulin receptor. Evidence for intermolecular transphosphorylation.

Taouis M, Levy-Toledano R, Roach P, Taylor SI, Gorden P. Taouis M, et al. Among authors: gorden p. J Biol Chem. 1994 Nov 4;269(44):27762-6. J Biol Chem. 1994. PMID: 7525562 Free article.

5

Insulin-induced activation of phosphatidyl inositol 3-kinase. Demonstration that the p85 subunit binds directly to the COOH terminus of the insulin receptor in intact cells.

Levy-Toledano R, Taouis M, Blaettler DH, Gorden P, Taylor SI. Levy-Toledano R, et al. Among authors: gorden p. J Biol Chem. 1994 Dec 9;269(49):31178-82. J Biol Chem. 1994. PMID: 7983060 Free article.

6

Substitution of glutamic acid for alanine 1135 in the putative "catalytic loop" of the tyrosine kinase domain of the human insulin receptor. A mutation that impairs proteolytic processing into subunits and inhibits receptor tyrosine kinase activity.

Cama A, de la Luz Sierra M, Quon MJ, Ottini L, Gorden P, Taylor SI. Cama A, et al. Among authors: gorden p. J Biol Chem. 1993 Apr 15;268(11):8060-9. J Biol Chem. 1993. PMID: 8096518 Free article.

7

Structural basis by which a recessive mutation in the alpha-subunit of the insulin receptor affects insulin binding.

Taouis M, Levy-Toledano R, Roach P, Taylor SI, Gorden P. Taouis M, et al. Among authors: gorden p. J Biol Chem. 1994 May 27;269(21):14912-8. J Biol Chem. 1994. PMID: 8195122 Free article.

8

Hormonal regulation of insulin receptor gene expression. Hydrocortisone and insulin act by different mechanisms.

Rouiller DG, McKeon C, Taylor SI, Gorden P. Rouiller DG, et al. Among authors: gorden p. J Biol Chem. 1988 Sep 15;263(26):13185-90. J Biol Chem. 1988. PMID: 3047118 Free article.

9

Biosynthesis and regulation of the insulin receptor.

Gorden P, Arakaki R, Collier E, Carpentier JL. Gorden P, et al. Yale J Biol Med. 1989 Sep-Oct;62(5):521-31. Yale J Biol Med. 1989. PMID: 2697986 Free PMC article. Review.

10

Mutational analysis of the NH2-terminal glycosylation sites of the insulin receptor alpha-subunit.

Caro LH, Ohali A, Gorden P, Collier E. Caro LH, et al. Among authors: gorden p. Diabetes. 1994 Feb;43(2):240-6. doi: 10.2337/diab.43.2.240. Diabetes. 1994. PMID: 8288048

Previously (Collier E, Carpentier J-L, Beitz L, Caro LHP, Taylor SI, Gorden P: Biochemistry 32:7818-23, 1993), site directed mutagenesis of the asparagine in the first four sites of N-linked glycosylation to glutamine resulted in a receptor that was retained in the …

Previously (Collier E, Carpentier J-L, Beitz L, Caro LHP, Taylor SI, Gorden P: Biochemistry 32:7818-23, 1993), site directed m …

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