Evin G - Search Results

1

Candidate gamma-secretases in the generation of the carboxyl terminus of the Alzheimer's disease beta A4 amyloid: possible involvement of cathepsin D.

Evin G, Cappai R, Li QX, Culvenor JG, Small DH, Beyreuther K, Masters CL. Evin G, et al. Biochemistry. 1995 Oct 31;34(43):14185-92. doi: 10.1021/bi00043a024. Biochemistry. 1995. PMID: 7578016

2

In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc.

Hoke DE, Tan JL, Ilaya NT, Culvenor JG, Smith SJ, White AR, Masters CL, Evin GM. Hoke DE, et al. Among authors: evin gm. FEBS J. 2005 Nov;272(21):5544-57. doi: 10.1111/j.1742-4658.2005.04950.x. FEBS J. 2005. PMID: 16262694 Free article.

3

Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease.

Holsinger RM, McLean CA, Beyreuther K, Masters CL, Evin G. Holsinger RM, et al. Among authors: evin g. Ann Neurol. 2002 Jun;51(6):783-6. doi: 10.1002/ana.10208. Ann Neurol. 2002. PMID: 12112088

4

Selecting cells with different Alzheimer's disease gamma-secretase activity using FACS. Differential effect on presenilin exon 9 gamma- and epsilon-cleavage.

Sernee MF, Evin G, Culvenor JG, Villadangos JA, Beyreuther K, Masters CL, Cappai R. Sernee MF, et al. Among authors: evin g. Eur J Biochem. 2003 Feb;270(3):495-506. doi: 10.1046/j.1432-1033.2003.03405.x. Eur J Biochem. 2003. PMID: 12542699 Free article.

5

Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.

Evin G, Zhu A, Holsinger RM, Masters CL, Li QX. Evin G, et al. J Neurosci Res. 2003 Nov 1;74(3):386-92. doi: 10.1002/jnr.10745. J Neurosci Res. 2003. PMID: 14598315

6

Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations.

Culvenor JG, Ilaya NT, Ryan MT, Canterford L, Hoke DE, Williamson NA, McLean CA, Masters CL, Evin G. Culvenor JG, et al. Among authors: evin g. Eur J Biochem. 2004 Jan;271(2):375-85. doi: 10.1046/j.1432-1033.2003.03936.x. Eur J Biochem. 2004. PMID: 14717705 Free article.

7

Transition-state analogue gamma-secretase inhibitors stabilize a 900 kDa presenilin/nicastrin complex.

Evin G, Canterford LD, Hoke DE, Sharples RA, Culvenor JG, Masters CL. Evin G, et al. Biochemistry. 2005 Mar 22;44(11):4332-41. doi: 10.1021/bi0481702. Biochemistry. 2005. PMID: 15766262

8

Inhibition of gamma-secretase as a therapeutic intervention for Alzheimer's disease: prospects, limitations and strategies.

Evin G, Sernee MF, Masters CL. Evin G, et al. CNS Drugs. 2006;20(5):351-72. doi: 10.2165/00023210-200620050-00002. CNS Drugs. 2006. PMID: 16696577 Review.

9

Paradoxical condensation of copper with elevated beta-amyloid in lipid rafts under cellular copper deficiency conditions: implications for Alzheimer disease.

Hung YH, Robb EL, Volitakis I, Ho M, Evin G, Li QX, Culvenor JG, Masters CL, Cherny RA, Bush AI. Hung YH, et al. Among authors: evin g. J Biol Chem. 2009 Aug 14;284(33):21899-21907. doi: 10.1074/jbc.M109.019521. Epub 2009 Jun 19. J Biol Chem. 2009. PMID: 19542222 Free PMC article.

10

BACE: Therapeutic target and potential biomarker for Alzheimer's disease.

Evin G, Barakat A, Masters CL. Evin G, et al. Int J Biochem Cell Biol. 2010 Dec;42(12):1923-6. doi: 10.1016/j.biocel.2010.08.017. Epub 2010 Sep 15. Int J Biochem Cell Biol. 2010. PMID: 20817005 Review.

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