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Pegylated long-acting human growth hormone possesses a promising once-weekly treatment profile, and multiple dosing is well tolerated in adult patients with growth hormone deficiency.
Søndergaard E, Klose M, Hansen M, Hansen BS, Andersen M, Feldt-Rasmussen U, Laursen T, Rasmussen MH, Christiansen JS. Søndergaard E, et al. Among authors: laursen t. J Clin Endocrinol Metab. 2011 Mar;96(3):681-8. doi: 10.1210/jc.2010-1931. Epub 2010 Dec 22. J Clin Endocrinol Metab. 2011. PMID: 21177789 Clinical Trial.
Incidence of GH deficiency - a nationwide study.
Stochholm K, Gravholt CH, Laursen T, Jørgensen JO, Laurberg P, Andersen M, Kristensen LØ, Feldt-Rasmussen U, Christiansen JS, Frydenberg M, Green A. Stochholm K, et al. Among authors: laursen t. Eur J Endocrinol. 2006 Jul;155(1):61-71. doi: 10.1530/eje.1.02191. Eur J Endocrinol. 2006. PMID: 16793951
Growth hormone administration stimulates energy expenditure and extrathyroidal conversion of thyroxine to triiodothyronine in a dose-dependent manner and suppresses circadian thyrotrophin levels: studies in GH-deficient adults.
Jørgensen JO, Møller J, Laursen T, Orskov H, Christiansen JS, Weeke J. Jørgensen JO, et al. Among authors: laursen t. Clin Endocrinol (Oxf). 1994 Nov;41(5):609-14. doi: 10.1111/j.1365-2265.1994.tb01826.x. Clin Endocrinol (Oxf). 1994. PMID: 7828350
332 results