Igarashi Y - Search Results

1

The signal modulator protein 14-3-3 is a target of sphingosine- or N,N-dimethylsphingosine-dependent kinase in 3T3(A31) cells.

Megidish T, White T, Takio K, Titani K, Igarashi Y, Hakomori S. Megidish T, et al. Among authors: igarashi y. Biochem Biophys Res Commun. 1995 Nov 22;216(3):739-47. doi: 10.1006/bbrc.1995.2684. Biochem Biophys Res Commun. 1995. PMID: 7488188

2

Cell membrane signaling as target in cancer therapy: inhibitory effect of N,N-dimethyl and N,N,N-trimethyl sphingosine derivatives on in vitro and in vivo growth of human tumor cells in nude mice.

Endo K, Igarashi Y, Nisar M, Zhou QH, Hakomori S. Endo K, et al. Among authors: igarashi y. Cancer Res. 1991 Mar 15;51(6):1613-8. Cancer Res. 1991. PMID: 1998952

Sphingosine (SPN) has been claimed to be a negative modulator of transmembrane signaling through protein kinase C (PK-C) or some yet unidentified mechanism [for review see Y. A. Hannun and R. M. Bell, Science (Washington DC), 243: 500-507, 1989]. N,N-Dimethylsphingosine (D …

Sphingosine (SPN) has been claimed to be a negative modulator of transmembrane signaling through protein kinase C (PK-C) or some yet unident …

3

A role of lyso-phosphatidylcholine in GM3-dependent inhibition of epidermal growth factor receptor autophosphorylation in A431 plasma membranes.

Igarashi Y, Kitamura K, Zhou QH, Hakomori S. Igarashi Y, et al. Biochem Biophys Res Commun. 1990 Oct 15;172(1):77-84. doi: 10.1016/s0006-291x(05)80175-5. Biochem Biophys Res Commun. 1990. PMID: 2171524

4

Enzymatic synthesis of N,N-dimethyl-sphingosine: demonstration of the sphingosine: N-methyltransferase in mouse brain.

Igarashi Y, Hakomori S. Igarashi Y, et al. Biochem Biophys Res Commun. 1989 Nov 15;164(3):1411-6. doi: 10.1016/0006-291x(89)91827-5. Biochem Biophys Res Commun. 1989. PMID: 2686639

5

Sphingosine-1-phosphate inhibits extracellular matrix protein-induced haptotactic motility but not adhesion of B16 mouse melanoma cells.

Sadahira Y, Zheng M, Ruan F, Hakomori S, Igarashi Y. Sadahira Y, et al. Among authors: igarashi y. FEBS Lett. 1994 Feb 28;340(1-2):99-103. doi: 10.1016/0014-5793(94)80180-0. FEBS Lett. 1994. PMID: 8119417 Free article.

6

Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): demonstration of cell type-specific response--a preliminary note.

Mazurek N, Megidish T, Hakomori S, Igarashi Y. Mazurek N, et al. Among authors: igarashi y. Biochem Biophys Res Commun. 1994 Jan 14;198(1):1-9. doi: 10.1006/bbrc.1994.1001. Biochem Biophys Res Commun. 1994. PMID: 8292009

7

N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets.

Yatomi Y, Ruan F, Megidish T, Toyokuni T, Hakomori S, Igarashi Y. Yatomi Y, et al. Among authors: igarashi y. Biochemistry. 1996 Jan 16;35(2):626-33. doi: 10.1021/bi9515533. Biochemistry. 1996. PMID: 8555236

8

In vitro and in vivo induction of apoptosis by sphingosine and N, N-dimethylsphingosine in human epidermoid carcinoma KB-3-1 and its multidrug-resistant cells.

Shirahama T, Sweeney EA, Sakakura C, Singhal AK, Nishiyama K, Akiyama S, Hakomori S, Igarashi Y. Shirahama T, et al. Among authors: igarashi y. Clin Cancer Res. 1997 Feb;3(2):257-64. Clin Cancer Res. 1997. PMID: 9815681

9

Endogenous substrates of sphingosine-dependent kinases (SDKs) are chaperone proteins: heat shock proteins, glucose-regulated proteins, protein disulfide isomerase, and calreticulin.

Megidish T, Takio K, Titani K, Iwabuchi K, Hamaguchi A, Igarashi Y, Hakomori S. Megidish T, et al. Among authors: igarashi y. Biochemistry. 1999 Mar 16;38(11):3369-78. doi: 10.1021/bi982548c. Biochemistry. 1999. PMID: 10079081

10

Effect of sphingosine and its N-methyl derivatives on oxidative burst, phagokinetic activity, and trans-endothelial migration of human neutrophils.

Kimura S, Kawa S, Ruan F, Nisar M, Sadahira Y, Hakomori S, Igarashi Y. Kimura S, et al. Among authors: igarashi y. Biochem Pharmacol. 1992 Oct 20;44(8):1585-95. doi: 10.1016/0006-2952(92)90476-y. Biochem Pharmacol. 1992. PMID: 1329769

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