Roques BP - Search Results

1

Mutation of Asp100 in the second transmembrane domain of the cholecystokinin B receptor increases antagonist binding and reduces signal transduction.

Jagerschmidt A, Guillaume N, Goudreau N, Maigret B, Roques BP. Jagerschmidt A, et al. Among authors: roques bp. Mol Pharmacol. 1995 Nov;48(5):783-9. Mol Pharmacol. 1995. PMID: 7476907

2

His381 of the rat CCKB receptor is essential for CCKB versus CCKA receptor antagonist selectivity.

Jagerschmidt A, Guillaume-Rousselet N, Vikland ML, Goudreau N, Maigret B, Roques BP. Jagerschmidt A, et al. Among authors: roques bp. Eur J Pharmacol. 1996 Jan 18;296(1):97-106. doi: 10.1016/0014-2999(95)00676-1. Eur J Pharmacol. 1996. PMID: 8720482

3

Binding sites and transduction process of the cholecystokininB receptor: involvement of highly conserved aromatic residues of the transmembrane domains evidenced by site-directed mutagenesis.

Jagerschmidt A, Guillaume N, Roques BP, Noble F. Jagerschmidt A, et al. Among authors: roques bp. Mol Pharmacol. 1998 May;53(5):878-85. Mol Pharmacol. 1998. PMID: 9584214

4

NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from Sos.

Goudreau N, Cornille F, Duchesne M, Parker F, Tocqué B, Garbay C, Roques BP. Goudreau N, et al. Among authors: roques bp. Nat Struct Biol. 1994 Dec;1(12):898-907. doi: 10.1038/nsb1294-898. Nat Struct Biol. 1994. PMID: 7773779

5

Identification and characterization of various cholecystokinin B receptor mRNA forms in rat brain tissue and partial determination of the cholecystokinin B receptor gene structure.

Jagerschmidt A, Popovici T, O'Donohue M, Roques BP. Jagerschmidt A, et al. Among authors: roques bp. J Neurochem. 1994 Oct;63(4):1199-206. doi: 10.1046/j.1471-4159.1994.63041199.x. J Neurochem. 1994. PMID: 7931273

6

Conformational analysis of CCK-B agonists using 1H-NMR and restrained molecular dynamics: comparison of biologically active Boc-Trp-(N-Me) Nle-Asp-Phe-NH2 and inactive Boc-Trp-(N-Me)Phe-Asp-Phe-NH2.

Goudreau N, Weng JH, Roques BP. Goudreau N, et al. Among authors: roques bp. Biopolymers. 1994 Feb;34(2):155-69. doi: 10.1002/bip.360340202. Biopolymers. 1994. PMID: 8142585

7

Comparative conformational analysis of CCK-B agonist Boc-Trp-Phg-Asp-(1-Nal)-NH2 and CCK1-B antagonist Boc-Trp-Phg-Asp-(1-Nal)-N(Me)2 using 1HNMR spectroscopy and restrained molecular dynamics.

Goudreau N, Weng JH, Roques BP. Goudreau N, et al. Among authors: roques bp. Arch Pharm (Weinheim). 1996 Apr;329(4):197-204. doi: 10.1002/ardp.19963290405. Arch Pharm (Weinheim). 1996. PMID: 8669984

8

Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor.

Blommaert AG, Dhôtel H, Ducos B, Durieux C, Goudreau N, Bado A, Garbay C, Roques BP. Blommaert AG, et al. Among authors: roques bp. J Med Chem. 1997 Feb 28;40(5):647-58. doi: 10.1021/jm9603072. J Med Chem. 1997. PMID: 9057851

9

Solid-phase synthesis, conformational analysis and in vitro cleavage of synthetic human synaptobrevin II 1-93 by tetanus toxin L chain.

Cornille F, Goudreau N, Ficheux D, Niemann H, Roques BP. Cornille F, et al. Among authors: roques bp. Eur J Biochem. 1994 May 15;222(1):173-81. doi: 10.1111/j.1432-1033.1994.tb18855.x. Eur J Biochem. 1994. PMID: 8200342 Free article.

10

Replacement of His23 by Cys in a zinc finger of HIV-1 NCp7 led to a change in 1H NMR-derived 3D structure and to a loss of biological activity.

Julian N, Demene H, Morellet N, Maigret B, Roques BP. Julian N, et al. Among authors: roques bp. FEBS Lett. 1993 Sep 27;331(1-2):43-8. doi: 10.1016/0014-5793(93)80294-5. FEBS Lett. 1993. PMID: 8405409 Free article.

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