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The Vasopressin Receptor 2 Mutant R137L Linked to the Nephrogenic Syndrome of Inappropriate Antidiuresis (NSIAD) Signals through an Alternative Pathway that Increases AQP2 Membrane Targeting Independently of S256 Phosphorylation.
Ranieri M, Venneri M, Pellegrino T, Centrone M, Di Mise A, Cotecchia S, Tamma G, Valenti G. Ranieri M, et al. Among authors: cotecchia s. Cells. 2020 May 29;9(6):1354. doi: 10.3390/cells9061354. Cells. 2020. PMID: 32486031 Free PMC article.
Gain-of-function mutations of the V2 vasopressin receptor in nephrogenic syndrome of inappropriate antidiuresis (NSIAD): a cell-based assay to assess constitutive water reabsorption.
Ranieri M, Tamma G, Pellegrino T, Vezzi V, Ambrosio C, Grò C, Di Mise A, Costa T, Valenti G, Cotecchia S. Ranieri M, et al. Among authors: cotecchia s. Pflugers Arch. 2019 Oct;471(10):1291-1304. doi: 10.1007/s00424-019-02307-x. Epub 2019 Sep 5. Pflugers Arch. 2019. PMID: 31486901
Ezrin directly interacts with AQP2 and promotes its endocytosis.
Li W, Jin WW, Tsuji K, Chen Y, Nomura N, Su L, Yui N, Arthur J, Cotecchia S, Paunescu TG, Brown D, Lu HAJ. Li W, et al. Among authors: cotecchia s. J Cell Sci. 2017 Sep 1;130(17):2914-2925. doi: 10.1242/jcs.204842. Epub 2017 Jul 28. J Cell Sci. 2017. PMID: 28754689 Free PMC article.
124 results